Jay S Desgrosellier
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Explore the profile of Jay S Desgrosellier including associated specialties, affiliations and a list of published articles.
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20
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2761
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Recent Articles
1.
Mugisha S, Baba S, Labhsetwar S, Dave D, Zakeri A, Klemke R, et al.
Oncogene
. 2025 Jan;
PMID: 39856330
Smoking plays an underappreciated role in breast cancer progression, increasing recurrence and mortality in patients. Here, we show that S100A8/A9 innate immune signaling is a molecular mechanism that identifies smoking-related...
2.
Baba S, Zakeri A, Desgrosellier J
Front Cell Dev Biol
. 2024 Sep;
12:1450614.
PMID: 39345336
Despite a critical role for tumor-initiating cancer stem cells (CSCs) in breast cancer progression, major questions remain about the properties and signaling pathways essential for their function. Recent discoveries highlighting...
3.
Baba S, Labhsetwar S, Klemke R, Desgrosellier J
Data Brief
. 2023 Oct;
51:109647.
PMID: 37840990
These data show the relative amount of chromosomal instability (CIN) in a diverse array of human breast cell types, including non-transformed mammary epithelial cells as well as cancer cell lines....
4.
Baba S, Sun Q, Mugisha S, Labhsetwar S, Klemke R, Desgrosellier J
Heliyon
. 2023 Oct;
9(9):e20182.
PMID: 37809421
Chromosomal instability (CIN) is critical for tumor evolution, yet its relationship with stemness is unclear. Here, we describe CIN as a key stress induced during tumor initiation that is uniquely...
5.
Sun Q, Wang Y, Officer A, Pecknold B, Lee G, Harismendy O, et al.
NPJ Breast Cancer
. 2022 Jan;
8(1):5.
PMID: 35027548
Breast cancer cells with stem-like properties are critical for tumor progression, yet much about these cells remains unknown. Here, we characterize a population of stem-like breast cancer cells expressing the...
6.
7.
Sun Q, Wang Y, Desgrosellier J
Cancer Lett
. 2019 May;
457:40-46.
PMID: 31078737
Breast cancer cells with stem cell properties play an important role in tumor progression and thus are key targets for therapy. Here, we show that combined Bcl-2/Src inhibition synergize to...
8.
Sun Q, Lesperance J, Wettersten H, Luterstein E, Derose Y, Welm A, et al.
J Clin Invest
. 2017 Dec;
128(1):531-544.
PMID: 29227280
Breast cancer cells with stem cell properties are key contributors to metastatic disease, and there remains a need to better understand and target these cells in human cancers. Here, we...
9.
Seguin L, Camargo M, Wettersten H, Kato S, Desgrosellier J, Von Schalscha T, et al.
Cancer Discov
. 2017 Sep;
7(12):1464-1479.
PMID: 28893801
Identifying the molecular basis for cancer cell dependence on oncogenes such as can provide new opportunities to target these addictions. Here, we identify a novel role for the carbohydrate-binding protein...
10.
Seguin L, Desgrosellier J, Weis S, Cheresh D
Trends Cell Biol
. 2015 Jan;
25(4):234-40.
PMID: 25572304
Interactions between cancer cells and their surroundings can trigger essential signaling cues that determine cell fate and influence the evolution of the malignant phenotype. As the primary receptors involved in...