Jay N Pieczynski
Overview
Explore the profile of Jay N Pieczynski including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
100
Followers
0
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Recent Articles
1.
Pieczynski J, Kee H
Biochem Mol Biol Educ
. 2020 Aug;
49(1):80-93.
PMID: 32777177
CRISPR-cas technology is being incorporated into undergraduate biology curriculum through lab experiences to immerse students in modern technology that is rapidly changing the landscape of science, medicine and agriculture. We...
2.
Magaletta M, Perkins K, Deuchler C, Pieczynski J
FASEB Bioadv
. 2020 Mar;
1(7):450-460.
PMID: 32123843
Microtubule plus-end directed trafficking is dominated by kinesin motors, yet kinesins differ in terms of cargo identity, movement rate, and distance travelled. Functional diversity of kinesins is especially apparent in...
3.
Pieczynski J, Deets A, McDuffee A, Kee H
Biochem Mol Biol Educ
. 2019 Jan;
47(2):145-155.
PMID: 30664332
Undergraduates learn that gene editing in diverse organisms is now possible. How targeted manipulation of genes and genomes is utilized in basic science and biomedicine to address biological questions is...
4.
Masyukova S, Landis D, Henke S, Williams C, Pieczynski J, Roszczynialski K, et al.
PLoS Genet
. 2016 Feb;
12(2):e1005841.
PMID: 26863025
Nephronophthisis (NPHP) is a ciliopathy in which genetic modifiers may underlie the variable penetrance of clinical features. To identify modifiers, a screen was conducted on C. elegans nphp-4(tm925) mutants. Mutations...
5.
Berbari N, Sharma N, Malarkey E, Pieczynski J, Boddu R, Gaertig J, et al.
Cytoskeleton (Hoboken)
. 2012 Nov;
70(1):24-31.
PMID: 23124988
Disruption of the primary cilium is associated with a growing number of human diseases collectively termed ciliopathies. Ciliopathies present with a broad range of clinical features consistent with the near...
6.
Harder J, Whiteman E, Pieczynski J, Liu C, Margolis B
Traffic
. 2012 May;
13(8):1170-85.
PMID: 22554228
During epithelial to mesenchymal transition (EMT), cells modulate expression of proteins resulting in loss of apical-basal polarity. Effectors of this EMT switch target the polarity protein Crumbs3a, a small transmembrane...
7.
Masyukova S, Winkelbauer M, Williams C, Pieczynski J, Yoder B
Hum Mol Genet
. 2011 May;
20(15):2942-54.
PMID: 21546380
A spectrum of complex oligogenic disorders called the ciliopathies have been connected to dysfunction of cilia. Among the ciliopathies are Nephronophthisis (NPHP), characterized by cystic kidney disease and retinal degeneration,...
8.
Straight S, Pieczynski J, Whiteman E, Liu C, Margolis B
J Biol Chem
. 2006 Oct;
281(49):37738-47.
PMID: 17012742
Mammalian Lin-7 forms a complex with several proteins, including PALS1, that have a role in polarity determination in epithelial cells. In this study we have found that loss of Lin-7...