Eileen L Whiteman
Overview
Explore the profile of Eileen L Whiteman including associated specialties, affiliations and a list of published articles.
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11
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646
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Recent Articles
1.
Whiteman E, Fan S, Harder J, Walton K, Liu C, Soofi A, et al.
Mol Cell Biol
. 2013 Oct;
34(1):43-56.
PMID: 24164893
First identified in Drosophila, the Crumbs (Crb) proteins are important in epithelial polarity, apical membrane formation, and tight junction (TJ) assembly. The conserved Crb intracellular region includes a FERM (band...
2.
Harder J, Whiteman E, Pieczynski J, Liu C, Margolis B
Traffic
. 2012 May;
13(8):1170-85.
PMID: 22554228
During epithelial to mesenchymal transition (EMT), cells modulate expression of proteins resulting in loss of apical-basal polarity. Effectors of this EMT switch target the polarity protein Crumbs3a, a small transmembrane...
3.
Fan S, Whiteman E, Hurd T, McIntyre J, Dishinger J, Liu C, et al.
Mol Biol Cell
. 2011 Oct;
22(23):4539-48.
PMID: 21998203
The small GTPase Ran and the importin proteins regulate nucleocytoplasmic transport. New evidence suggests that Ran GTP and the importins are also involved in conveying proteins into cilia. In this...
4.
Schluter M, Pfarr C, Pieczynski J, Whiteman E, Hurd T, Fan S, et al.
Mol Biol Cell
. 2009 Sep;
20(22):4652-63.
PMID: 19776356
Although lumen generation has been extensively studied through so-called cyst-formation assays in Madin-Darby canine kidney (MDCK) cells, an underlying mechanism that leads to the initial appearance of a solitary lumen...
5.
Straight S, Pieczynski J, Whiteman E, Liu C, Margolis B
J Biol Chem
. 2006 Oct;
281(49):37738-47.
PMID: 17012742
Mammalian Lin-7 forms a complex with several proteins, including PALS1, that have a role in polarity determination in epithelial cells. In this study we have found that loss of Lin-7...
6.
Bach T, Kerr W, Wang Y, Bauman E, Kine P, Whiteman E, et al.
Blood
. 2006 Sep;
109(3):1147-55.
PMID: 17008542
Pleckstrin-2 is composed of 2 pleckstrin homology (PH) domains and a disheveled-Egl-10-pleckstrin (DEP) domain. A lipid-binding assay revealed that pleckstrin-2 binds with greatest affinity to D3 and D5 phosphoinositides. Pleckstrin-2...
7.
Yoshino A, Setty S, Poynton C, Whiteman E, Saint-Pol A, Burd C, et al.
J Cell Sci
. 2005 May;
118(Pt 10):2279-93.
PMID: 15870108
tGolgin-1 (trans-Golgi p230, golgin-245) is a member of a family of large peripheral membrane proteins that associate with the trans-Golgi network (TGN) via a C-terminal GRIP domain. Some GRIP-domain proteins...
8.
Steppan C, Wang J, Whiteman E, Birnbaum M, Lazar M
Mol Cell Biol
. 2005 Feb;
25(4):1569-75.
PMID: 15684405
Resistin is an adipocyte hormone that modulates glucose homeostasis. Here we show that in 3T3-L1 adipocytes, resistin attenuates multiple effects of insulin, including insulin receptor (IR) phosphorylation, IR substrate 1...
9.
Whiteman E, Chen J, Birnbaum M
Endocrinology
. 2003 Aug;
144(9):3811-20.
PMID: 12933652
Insulin is unique among growth factors and hormones in its ability to control metabolic functions such as the stimulation of glucose uptake and glucose transporter (GLUT4) translocation in physiological target...
10.