Corey L Williams
Overview
Explore the profile of Corey L Williams including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
708
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Uytingco C, Williams C, Xie C, Shively D, Green W, Ukhanov K, et al.
J Cell Sci
. 2019 Jan;
132(5).
PMID: 30665891
Bardet-Beidl syndrome (BBS) manifests from genetic mutations encoding for one or more BBS proteins. BBS4 loss impacts olfactory ciliation and odor detection, yet the cellular mechanisms remain unclear. Here, we...
2.
Jensen V, Lambacher N, Li C, Mohan S, Williams C, Inglis P, et al.
EMBO Rep
. 2018 Nov;
19(12).
PMID: 30429209
Genetic disorders caused by cilia dysfunction, termed ciliopathies, frequently involve the intraflagellar transport (IFT) system. Mutations in IFT subunits-including IFT-dynein motor DYNC2H1-impair ciliary structures and Hedgehog signalling, typically leading to...
3.
Williams C, Uytingco C, Green W, McIntyre J, Ukhanov K, Zimmerman A, et al.
Mol Ther
. 2017 Feb;
25(4):904-916.
PMID: 28237838
Olfactory dysfunction is a pervasive but underappreciated health concern that affects personal safety and quality of life. Patients with olfactory dysfunctions have limited therapeutic options, particularly those involving congenital diseases....
4.
Masyukova S, Landis D, Henke S, Williams C, Pieczynski J, Roszczynialski K, et al.
PLoS Genet
. 2016 Feb;
12(2):e1005841.
PMID: 26863025
Nephronophthisis (NPHP) is a ciliopathy in which genetic modifiers may underlie the variable penetrance of clinical features. To identify modifiers, a screen was conducted on C. elegans nphp-4(tm925) mutants. Mutations...
5.
Williams C, McIntyre J, Norris S, Jenkins P, Zhang L, Pei Q, et al.
Nat Commun
. 2014 Dec;
5:5813.
PMID: 25504142
Cilia dysfunction underlies a class of human diseases with variable penetrance in different organ systems. Across eukaryotes, intraflagellar transport (IFT) facilitates cilia biogenesis and cargo trafficking, but our understanding of...
6.
McIntyre J, Williams C, Martens J
Trends Biotechnol
. 2013 Apr;
31(6):355-63.
PMID: 23601268
Alterations in cilia formation or function underlie a growing class of pleiotropic disorders termed ciliopathies. The genetic basis of ciliopathies is remarkably complex, with an incomplete but expanding list of...
7.
McIntyre J, Davis E, Joiner A, Williams C, Tsai I, Jenkins P, et al.
Nat Med
. 2012 Sep;
18(9):1423-8.
PMID: 22941275
Cilia are evolutionarily conserved microtubule-based organelles that are crucial for diverse biological functions, including motility, cell signaling and sensory perception. In humans, alterations in the formation and function of cilia...
8.
Masyukova S, Winkelbauer M, Williams C, Pieczynski J, Yoder B
Hum Mol Genet
. 2011 May;
20(15):2942-54.
PMID: 21546380
A spectrum of complex oligogenic disorders called the ciliopathies have been connected to dysfunction of cilia. Among the ciliopathies are Nephronophthisis (NPHP), characterized by cystic kidney disease and retinal degeneration,...
9.
Williams C, Li C, Kida K, Inglis P, Mohan S, Semenec L, et al.
J Cell Biol
. 2011 Mar;
192(6):1023-41.
PMID: 21422230
Meckel-Gruber syndrome (MKS), nephronophthisis (NPHP), and related ciliopathies present with overlapping phenotypes and display considerable allelism between at least twelve different genes of largely unexplained function. We demonstrate that the...
10.
Williams C, Masyukova S, Yoder B
J Am Soc Nephrol
. 2010 Feb;
21(5):782-93.
PMID: 20150540
Cilia dysfunction contributes to renal cyst formation in multiple human syndromes including nephronophthisis (NPHP), Meckel-Gruber syndrome (MKS), Joubert syndrome (JBTS), and Bardet-Beidl syndrome (BBS). Although genetically heterogeneous, these diseases share...