Jau-Yi Li
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Explore the profile of Jau-Yi Li including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
1560
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Recent Articles
11.
Robinson J, Li J, Walker L, Tyagi A, Reott M, Yu M, et al.
J Bone Miner Res
. 2014 Nov;
30(4):695-705.
PMID: 25359628
T cells are known to potentiate the bone anabolic activity of intermittent parathyroid hormone (iPTH) treatment. One of the involved mechanisms is increased T cell secretion of Wnt10b, a potent...
12.
Li J, Walker L, Tyagi A, Adams J, Weitzmann M, Pacifici R
J Bone Miner Res
. 2013 Dec;
29(1):43-54.
PMID: 24357520
Both blunted osteocytic production of the Wnt inhibitor sclerostin (Scl) and increased T-cell production of the Wnt ligand Wnt10b contribute to the bone anabolic activity of intermittent parathyroid hormone (iPTH)...
13.
Li J, Adams J, Calvi L, Lane T, Weitzmann M, Pacifici R
Blood
. 2013 Aug;
122(14):2346-57.
PMID: 23954891
Estrogen deficiency expands hemopoietic stem and progenitor cells (HSPCs) and mature blood lineages, but the involved mechanism and the affected HSPC populations are mostly unknown. Here we show that ovariectomy...
14.
Li J, Adams J, Calvi L, Lane T, DiPaolo R, Weitzmann M, et al.
Blood
. 2012 Sep;
120(22):4352-62.
PMID: 22955916
Intermittent parathyroid hormone (iPTH) treatment expands hemopoietic stem and progenitor cells (HSPCs), but the involved mechanisms and the affected HSPC populations are mostly unknown. Here we show that T cells...
15.
Bedi B, Li J, Tawfeek H, Baek K, Adams J, Vangara S, et al.
Proc Natl Acad Sci U S A
. 2012 Mar;
109(12):E725-33.
PMID: 22393015
Intermittent parathyroid hormone (iPTH) treatment stimulates T-cell production of the osteogenic Wnt ligand Wnt10b, a factor required for iPTH to activate Wnt signaling in osteoblasts and stimulate bone formation. However,...
16.
Ovariectomy disregulates osteoblast and osteoclast formation through the T-cell receptor CD40 ligand
Li J, Tawfeek H, Bedi B, Yang X, Adams J, Gao K, et al.
Proc Natl Acad Sci U S A
. 2010 Dec;
108(2):768-73.
PMID: 21187391
The bone loss induced by ovariectomy (ovx) has been linked to increased production of osteoclastogenic cytokines by bone marrow cells, including T cells and stromal cells (SCs). It is presently...
17.
Tawfeek H, Bedi B, Li J, Adams J, Kobayashi T, Weitzmann M, et al.
PLoS One
. 2010 Sep;
5(8):e12290.
PMID: 20808842
Background: Hyperparathyroidism in humans and continuous parathyroid hormone (cPTH) treatment in mice cause bone loss by regulating the production of RANKL and OPG by stromal cells (SCs) and osteoblasts (OBs)....
18.
Bedi B, Li J, Grassi F, Tawfeek H, Weitzmann M, Pacifici R
Ann N Y Acad Sci
. 2010 Apr;
1192:215-21.
PMID: 20392239
T cells are required for continuous parathyroid hormone (cPTH) treatment to induce bone loss as they sensitize stromal cells to PTH through CD40 ligand (CD40L), a surface molecule of activated...
19.
Terauchi M, Li J, Bedi B, Baek K, Tawfeek H, Galley S, et al.
Cell Metab
. 2009 Sep;
10(3):229-40.
PMID: 19723499
Intermittent administration of parathyroid hormone (iPTH) is used to treat osteoporosis because it improves bone architecture and strength, but the underlying cellular and molecular mechanisms are unclear. Here, we show...
20.
Gao Y, Wu X, Terauchi M, Li J, Grassi F, Galley S, et al.
Cell Metab
. 2008 Aug;
8(2):132-45.
PMID: 18680714
Parathyroid hormone (PTH) promotes bone catabolism by targeting bone marrow (BM) stromal cells (SCs) and their osteoblastic progeny. Here we show that a continuous infusion of PTH that mimics hyperparathyroidism...