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Abdul Malik Tyagi

Explore the profile of Abdul Malik Tyagi including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 1064
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Recent Articles
1.
Umar S, Cronin O, Tyagi A
Front Endocrinol (Lausanne) . 2024 Jan; 14:1346156. PMID: 38250740
No abstract available.
2.
Tyagi A
Endocrinol Diabetes Metab . 2023 Jul; 7(1):e440. PMID: 37505196
Introduction: Gut microbiota (GM) is the collection of small organisms such as bacteria, fungi, bacteriophages and protozoans living in the intestine in symbiotics relation within their host. GM regulates host...
3.
Tyagi A, Umar S
Front Endocrinol (Lausanne) . 2022 Sep; 13:991989. PMID: 36176471
No abstract available.
4.
Yu M, Pal S, Paterson C, Li J, Tyagi A, Adams J, et al.
J Clin Invest . 2021 Feb; 131(4). PMID: 33586672
Estrogen deficiency causes a gut microbiome-dependent expansion of BM Th17 cells and TNF-α-producing T cells. The resulting increased BM levels of IL-17a (IL-17) and TNF stimulate RANKL expression and activity,...
5.
Tyagi A, Darby T, Hsu E, Yu M, Pal S, Dar H, et al.
Elife . 2021 Jan; 10. PMID: 33432923
Genetic factors account for the majority of the variance of human bone mass, but the contribution of non-genetic factors remains largely unknown. By utilizing maternal/offspring transmission, cohabitation, or fecal material...
6.
Yu M, Tyagi A, Li J, Adams J, Denning T, Weitzmann M, et al.
Nat Commun . 2020 Jan; 11(1):468. PMID: 31980603
Bone loss is a frequent but not universal complication of hyperparathyroidism. Using antibiotic-treated or germ-free mice, we show that parathyroid hormone (PTH) only caused bone loss in mice whose microbiota...
7.
Li J, Yu M, Pal S, Tyagi A, Dar H, Adams J, et al.
J Clin Invest . 2020 Jan; 130(4):1767-1781. PMID: 31917685
Parathyroid hormone (PTH) is a critical regulator of skeletal development that promotes both bone formation and bone resorption. Using microbiota depletion by wide-spectrum antibiotics and germ-free (GF) female mice, we...
8.
Tyagi A, Yu M, Darby T, Vaccaro C, Li J, Owens J, et al.
Immunity . 2018 Nov; 49(6):1116-1131.e7. PMID: 30446387
Nutritional supplementation with probiotics can prevent pathologic bone loss. Here we examined the impact of supplementation with Lactobacillus rhamnosus GG (LGG) on bone homeostasis in eugonadic young mice. Micro-computed tomography...
9.
Li J, Yu M, Tyagi A, Vaccaro C, Hsu E, Adams J, et al.
J Bone Miner Res . 2018 Nov; 34(2):349-360. PMID: 30399207
Primary hyperparathyroidism (PHPT) is a condition where elevated PTH levels lead to bone loss, in part through increased production of the osteoclastogenic factor IL-17A, by bone marrow (BM) T-helper 17...
10.
Yu M, DAmelio P, Tyagi A, Vaccaro C, Li J, Hsu E, et al.
EMBO Rep . 2017 Nov; 19(1):156-171. PMID: 29158349
Teriparatide is a bone anabolic treatment for osteoporosis, modeled in animals by intermittent PTH (iPTH) administration, but the cellular and molecular mechanisms of action of iPTH are largely unknown. Here,...