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Jan Sjovall

Explore the profile of Jan Sjovall including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 816
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Recent Articles
21.
Lengqvist J, Alvelius G, Jornvall H, Sjovall J, Perlmann T, Griffiths W
J Am Soc Mass Spectrom . 2005 Aug; 16(10):1631-40. PMID: 16085421
Accurate mass measurements are often used in the structural determination of unknown compounds of low molecular mass (i.e., below approximately 500 Da). Recently, it has been shown that accurate mass...
22.
von Bahr S, Bjorkhem I, Hooft F, Alvelius G, Nemeth A, Sjovall J, et al.
J Pediatr Gastroenterol Nutr . 2005 Mar; 40(4):481-6. PMID: 15795599
Background: Inborn errors of bile acid synthesis are rare but potentially treatable causes of neonatal cholestasis. We here present a cholestatic infant with an ongoing cytomegalovirus infection who despite intensive...
23.
Sjovall J
Lipids . 2005 Jan; 39(8):703-22. PMID: 15638239
Cholesterol and its metabolites, e.g., steroid hormones and bile acids, constitute a class of compounds of great biological importance. Their chemistry, biochemistry, and regulation in the body have been intensely...
24.
Liere P, Pianos A, Eychenne B, Cambourg A, Liu S, Griffiths W, et al.
J Lipid Res . 2004 Sep; 45(12):2287-302. PMID: 15342680
A new sample preparation method coupled to GC-MS analysis was developed and validated for quantification of sulfate esters of pregnenolone (PREG-S) and dehydroepiandrosterone (DHEA-S) in rat brain. Using a solid-phase...
25.
Griffiths W, Alvelius G, Liu S, Sjovall J
Eur J Mass Spectrom (Chichester) . 2004 Apr; 10(1):63-88. PMID: 15100480
Neutral oxosteroids have been derivatised with Girard T and P hydrazine reagents to give the corresponding Girard hydrazone quaternary ammonium salts. Both Girard T (GT) and Girard P (GP) hydrazones...
26.
Lengqvist J, Mata de Urquiza A, Bergman A, Willson T, Sjovall J, Perlmann T, et al.
Mol Cell Proteomics . 2004 Apr; 3(7):692-703. PMID: 15073272
Nuclear receptors (NRs) constitute a large and highly conserved family of ligand-activated transcription factors that regulate diverse biological processes such as development, metabolism, and reproduction. As such, NRs have become...
27.
Liu S, Sjovall J, Griffiths W
Anal Chem . 2003 Nov; 75(21):5835-46. PMID: 14588024
A method designed for the analysis of sulfated neurosteroids and unconjugated ketonic neurosteroids in rat brain using nanoscale liquid chromatography-electrospray (nano-LC-ES) mass spectrometry is described. Neurosteroids in rat brain tissue...
28.
Griffiths W, Liu S, Alvelius G, Sjovall J
Rapid Commun Mass Spectrom . 2003 Apr; 17(9):924-35. PMID: 12717765
The identification, quantification and localisation of steroids in biological fluids and tissues are subjects of considerable importance. Not only do steroids have classical hormonal properties via binding to nuclear receptors,...
29.
Liu S, Griffiths W, Sjovall J
Anal Chem . 2003 Mar; 75(4):1022-30. PMID: 12622400
It is well-established that electrochemical reactions can occur within the capillary of an electrospray (ES) devise coupled to a mass spectrometer. In fact, such reactions must occur to maintain charge...
30.
Liu S, Griffiths W, Sjovall J
Anal Chem . 2003 Mar; 75(4):791-7. PMID: 12622368
A new procedure for capillary liquid chromatography-electrospray (CLC-ES) mass spectrometry is described. Using this procedure, coupling of a CLC column to a low-flow-rate ES interface is made simple. A 5-cm...