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Martin Hornshaw

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Articles 17
Citations 324
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Recent Articles
1.
Dunn Z, Bohman P, Quinteros A, Sauerborn B, Milman F, Patel M, et al.
Anal Chem . 2023 Nov; 95(49):18130-18138. PMID: 38015205
Real-time monitoring of biopharmaceutical reactors is becoming increasingly important as the processes become more complex. During the continuous manufacturing of monoclonal antibodies (mAbs), the desired mAb product is continually created...
2.
Aldrovandi M, Hinz C, Lauder S, Podmore H, Hornshaw M, Slatter D, et al.
Redox Biol . 2017 Feb; 11:663-672. PMID: 28160743
Activated platelets generate an eicosanoid proposed to be 8-hydroxy-9,10-dioxolane A3 (DXA). Herein, we demonstrate that significant amounts of DXA are rapidly attached to phosphatidylethanolamine (PE) forming four esterified eicosanoids, 16:0p,...
3.
Aldrovandi M, Hammond V, Podmore H, Hornshaw M, Clark S, Marnett L, et al.
J Lipid Res . 2013 Jul; 54(11):3085-97. PMID: 23883581
Oxidized phospholipids (oxPLs) generated nonenzymatically display pleiotropic biological actions in inflammation. Their generation by cellular cyclooxygenases (COXs) is currently unknown. To determine whether platelets generate prostaglandin (PG)-containing oxPLs, then characterize...
4.
Pannee J, Portelius E, Oppermann M, Atkins A, Hornshaw M, Zegers I, et al.
J Alzheimers Dis . 2012 Oct; 33(4):1021-32. PMID: 23076076
Cerebrospinal fluid (CSF) biomarkers for Alzheimer's disease (AD) are increasingly used in research centers, clinical trials, and clinical settings. However, their broad-scale use is hampered by lack of standardization across...
5.
Oppermann M, Damoc N, Crone C, Moehring T, Muenster H, Hornshaw M
Methods Mol Biol . 2012 Feb; 860:145-56. PMID: 22351176
The degree of precision in measuring accurate masses in LC MS/MS-based metabolomics experiments is a determinant in the successful identification of the metabolites present in the original extract. Using the...
6.
Wang H, Wang L, Zhou M, Yang M, Ma C, Chen T, et al.
Biochimie . 2011 Dec; 94(3):891-9. PMID: 22197669
Amphibian skin secretions are, for the most part, complex peptidomes. While many peptide components have been biologically- and structurally-characterised into discrete "families", some of which are analogues of endogenous vertebrate...
7.
Scigelova M, Hornshaw M, Giannakopulos A, Makarov A
Mol Cell Proteomics . 2011 Jul; 10(7):M111.009431. PMID: 21742802
This article provides an introduction to Fourier transform-based mass spectrometry. The key performance characteristics of Fourier transform-based mass spectrometry, mass accuracy and resolution, are presented in the view of how...
8.
Li X, Feng W, Zhou M, Ma C, Chen T, Zeller M, et al.
Biochimie . 2011 Jun; 93(9):1537-42. PMID: 21624426
Amphibian skin secretions are established sources of bioactive peptides. Here we describe the isolation, structural and pharmacological characterisation of a novel vasoconstrictor peptide from the skin secretion of the African...
9.
Seppala U, Dauly C, Robinson S, Hornshaw M, Larsen J, Ipsen H
J Proteome Res . 2011 Jan; 10(4):2113-22. PMID: 21241049
Products for specific diagnosis and immunotherapy of IgE-mediated allergies are currently based on natural extracts. Quantification of major allergen content is an important aspect of standardization as important allergens particularly...
10.
Chen H, Wang L, Zeller M, Hornshaw M, Wu Y, Zhou M, et al.
Mol Immunol . 2010 Nov; 48(4):442-51. PMID: 21040978
From defensive skin secretions acquired from two species of African hyperoliid frogs, Kassina maculata and Kassina senegalensis, we have isolated two structurally related, C-terminally amidated tridecapeptides of novel primary structure...