Jan H Lui
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Explore the profile of Jan H Lui including associated specialties, affiliations and a list of published articles.
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19
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2764
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Recent Articles
1.
Clarke M, Remesal L, Lentz L, Tan D, Young D, Thapa S, et al.
Mol Ther
. 2024 Feb;
32(4):935-951.
PMID: 38327047
Angelman syndrome (AS), an early-onset neurodevelopmental disorder characterized by abnormal gait, intellectual disabilities, and seizures, occurs when the maternal allele of the UBE3A gene is disrupted, since the paternal allele...
2.
Pederick D, Lui J, Gingrich E, Xu C, Wagner M, Liu Y, et al.
Science
. 2021 Jun;
372(6546):1068-1073.
PMID: 34083484
Mammalian medial and lateral hippocampal networks preferentially process spatial- and object-related information, respectively. However, the mechanisms underlying the assembly of such parallel networks during development remain largely unknown. Our study...
3.
Yuste R, Hawrylycz M, Aalling N, Aguilar-Valles A, Arendt D, Armananzas R, et al.
Nat Neurosci
. 2021 Mar;
24(4):612.
PMID: 33742182
No abstract available.
4.
Lui J, Nguyen N, Grutzner S, Darmanis S, Peixoto D, Wagner M, et al.
Cell
. 2020 Dec;
184(2):489-506.e26.
PMID: 33338423
Single-cell transcriptomics has been widely applied to classify neurons in the mammalian brain, while systems neuroscience has historically analyzed the encoding properties of cortical neurons without considering cell types. Here...
5.
Yuste R, Hawrylycz M, Aalling N, Aguilar-Valles A, Arendt D, Arnedillo R, et al.
Nat Neurosci
. 2020 Dec;
24(4):613.
PMID: 33277642
No abstract available.
6.
Yuste R, Hawrylycz M, Aalling N, Aguilar-Valles A, Arendt D, Armananzas R, et al.
Nat Neurosci
. 2020 Aug;
23(12):1456-1468.
PMID: 32839617
To understand the function of cortical circuits, it is necessary to catalog their cellular diversity. Past attempts to do so using anatomical, physiological or molecular features of cortical cells have...
7.
Friedmann D, Pun A, Adams E, Lui J, Kebschull J, Grutzner S, et al.
Proc Natl Acad Sci U S A
. 2020 May;
117(20):11068-11075.
PMID: 32358193
The projection targets of a neuronal population are a key feature of its anatomical characteristics. Historically, tissue sectioning, confocal microscopy, and manual scoring of specific regions of interest have been...
8.
Raju C, Spatazza J, Stanco A, Larimer P, Sorrells S, Kelley K, et al.
Cereb Cortex
. 2017 Apr;
28(6):1946-1958.
PMID: 28449024
The neocortex of primates, including humans, contains more abundant and diverse inhibitory neurons compared with rodents, but the molecular foundations of these observations are unknown. Through integrative gene coexpression analysis,...
9.
Liu S, Nowakowski T, Pollen A, Lui J, Horlbeck M, Attenello F, et al.
Genome Biol
. 2016 Apr;
17:67.
PMID: 27081004
Background: Long non-coding RNAs (lncRNAs) comprise a diverse class of transcripts that can regulate molecular and cellular processes in brain development and disease. LncRNAs exhibit cell type- and tissue-specific expression,...
10.
Lui J, Nowakowski T, Pollen A, Javaherian A, Kriegstein A, Oldham M
Nature
. 2014 Nov;
515(7526):264-8.
PMID: 25391964
Evolutionary expansion of the human neocortex underlies many of our unique mental abilities. This expansion has been attributed to the increased proliferative potential of radial glia (RG; neural stem cells)...