Javier DeFelipe
Overview
Explore the profile of Javier DeFelipe including associated specialties, affiliations and a list of published articles.
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206
Citations
6904
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Recent Articles
1.
Plaza-Alonso S, Cano-Astorga N, DeFelipe J, Alonso-Nanclares L
Elife
. 2025 Jan;
14.
PMID: 39882848
The entorhinal cortex (EC) plays a pivotal role in memory function and spatial navigation, connecting the hippocampus with the neocortex. The EC integrates a wide range of cortical and subcortical...
2.
Gonzalez-Riano C, Leon-Espinosa G, Regalado-Reyes M, Garcia A, DeFelipe J, Barbas C
J Chromatogr A
. 2025 Jan;
1743:465692.
PMID: 39864223
Mammalian hibernation offers a unique model for exploring neuroprotective mechanisms relevant to neurodegenerative diseases. In this study, we employed untargeted lipidomics with iterative tandem mass spectrometry (MS/MS) to profile the...
3.
Covelo J, Camassa A, Sanchez-Sanchez J, Manasanch A, Porta L, Cancino-Fuentes N, et al.
Prog Neurobiol
. 2025 Jan;
246:102719.
PMID: 39848562
Elucidating human cerebral cortex function is essential for understanding the physiological basis of both healthy and pathological brain states. We obtained extracellular local field potential recordings from slices of neocortical...
4.
Kanari L, Shi Y, Arnaudon A, Barros-Zulaica N, Benavides-Piccione R, Coggan J, et al.
bioRxiv
. 2025 Jan;
PMID: 39763990
The organizational principles that distinguish the human brain from other species have been a long-standing enigma in neuroscience. Focusing on the uniquely evolved human cortical layers 2 and 3, we...
5.
Merino-Serrais P, Soria J, Arrabal C, Ortigado-Lopez A, Esparza M, Munoz A, et al.
Exp Neurol
. 2024 Nov;
383:115049.
PMID: 39522802
Tau has a wide variety of essential functions in the brain, but this protein also plays a determining role in the development of Alzheimer's disease (AD) and other neurodegenerative diseases...
6.
Makarova J, Toledano R, Blazquez-Llorca L, Sanchez-Herraez E, Gil-Nagel A, DeFelipe J, et al.
J Neurosci
. 2024 Oct;
45(1).
PMID: 39481886
Intracranial potentials are used as functional biomarkers of neural networks. As potentials spread away from the source populations, they become mixed in the recordings. In humans, interindividual differences in the...
7.
Cano-Astorga N, Plaza-Alonso S, DeFelipe J, Alonso-Nanclares L
Cereb Cortex
. 2024 Aug;
34(8.
PMID: 39106175
Functional and structural studies investigating macroscopic connectivity in the human cerebral cortex suggest that high-order associative regions exhibit greater connectivity compared to primary ones. However, the synaptic organization of these...
8.
Turegano-Lopez M, de Las Pozas F, Santuy A, Rodriguez J, DeFelipe J, Merchan-Perez A
Commun Biol
. 2024 Jul;
7(1):796.
PMID: 38951162
The highly complex structure of the brain requires an approach that can unravel its connectivity. Using volume electron microscopy and a dedicated software we can trace and measure all nerve...
9.
Benavides-Piccione R, Blazquez-Llorca L, Kastanauskaite A, Fernaud-Espinosa I, Tapia-Gonzalez S, DeFelipe J
Cereb Cortex
. 2024 May;
34(5.
PMID: 38745556
The basic building block of the cerebral cortex, the pyramidal cell, has been shown to be characterized by a markedly different dendritic structure among layers, cortical areas, and species. Functionally,...
10.
Cano-Astorga N, Plaza-Alonso S, Turegano-Lopez M, Rodrigo-Rodriguez J, Merchan-Perez A, DeFelipe J
Front Neuroanat
. 2024 Apr;
18:1348032.
PMID: 38645671
The brain contains thousands of millions of synapses, exhibiting diverse structural, molecular, and functional characteristics. However, synapses can be classified into two primary morphological types: Gray's type I and type...