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Jan-Michael Peters

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Articles 140
Citations 14216
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Recent Articles
1.
Barth R, Davidson I, van der Torre J, Taschner M, Gruber S, Peters J, et al.
Cell . 2025 Jan; 188(3):749-763.e21. PMID: 39824185
Structural maintenance of chromosomes (SMC) complexes organize the genome via DNA loop extrusion. Although some SMCs were reported to do so symmetrically, reeling DNA from both sides into the extruded...
2.
Brunner A, Morero N, Zhang W, Hossain M, Lampe M, Pflaumer H, et al.
J Cell Biol . 2025 Jan; 224(3). PMID: 39786339
How cells establish the interphase genome organization after mitosis is incompletely understood. Using quantitative and super-resolution microscopy, we show that the transition from a Condensin to a Cohesin-based genome organization...
3.
Tang W, Costantino L, Stocsits R, Wutz G, Ladurner R, Hudecz O, et al.
EMBO J . 2025 Jan; 44(3):736-766. PMID: 39748119
Genomic DNA is assembled into chromatin by histones, and extruded into loops by cohesin. These mechanisms control important genomic functions, but whether histones and cohesin cooperate in genome regulation is...
4.
Janissen R, Barth R, Davidson I, Peters J, Dekker C
Sci Adv . 2024 Dec; 10(50):eadt1832. PMID: 39671477
Eukaryotes carry three types of structural maintenance of chromosome (SMC) protein complexes, condensin, cohesin, and SMC5/6, which are ATP-dependent motor proteins that remodel the genome via DNA loop extrusion (LE)....
5.
Brunner A, Morero N, Zhang W, Hossain M, Lampe M, Pflaumer H, et al.
bioRxiv . 2024 Jun; PMID: 38854067
How cells establish the interphase genome organization after mitosis is incompletely understood. Using quantitative and super-resolution microscopy, we show that the transition from a Condensin to a Cohesin-based genome organization...
6.
Prusen Mota I, Galova M, Schleiffer A, Nguyen T, Kovacikova I, Farias Saad C, et al.
Nat Commun . 2024 Jun; 15(1):4729. PMID: 38830897
Cohesin mediates sister chromatid cohesion to enable chromosome segregation and DNA damage repair. To perform these functions, cohesin needs to be protected from WAPL, which otherwise releases cohesin from DNA....
7.
Jessberger G, Varnai C, Stocsits R, Tang W, Stary G, Peters J
Genome Res . 2023 Dec; 33(12):2094-2107. PMID: 38129077
Paternal genomes are compacted during spermiogenesis and decompacted following fertilization. These processes are fundamental for inheritance but incompletely understood. We analyzed these processes in the frog , whose sperm can...
8.
Dekker C, Haering C, Peters J, Rowland B
Science . 2023 Nov; 382(6671):646-648. PMID: 37943927
A potential mechanism of DNA loop extrusion by molecular motors is discussed.
9.
Nagasaka K, Davidson I, Stocsits R, Tang W, Wutz G, Batty P, et al.
Mol Cell . 2023 Aug; 83(17):3049-3063.e6. PMID: 37591243
Cohesin connects CTCF-binding sites and other genomic loci in cis to form chromatin loops and replicated DNA molecules in trans to mediate sister chromatid cohesion. Whether cohesin uses distinct or...
10.
Barth R, Pradhan B, Kim E, Davidson I, van der Torre J, Peters J, et al.
Sci Rep . 2023 Jul; 13(1):11616. PMID: 37463951
No abstract available.