Rene Ladurner
Overview
Explore the profile of Rene Ladurner including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
920
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0
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Recent Articles
1.
Tang W, Costantino L, Stocsits R, Wutz G, Ladurner R, Hudecz O, et al.
EMBO J
. 2025 Jan;
44(3):736-766.
PMID: 39748119
Genomic DNA is assembled into chromatin by histones, and extruded into loops by cohesin. These mechanisms control important genomic functions, but whether histones and cohesin cooperate in genome regulation is...
2.
Wutz G, Ladurner R, St Hilaire B, Stocsits R, Nagasaka K, Pignard B, et al.
Elife
. 2020 Feb;
9.
PMID: 32065581
Eukaryotic genomes are folded into loops. It is thought that these are formed by cohesin complexes extrusion, either until loop expansion is arrested by CTCF or until cohesin is removed...
3.
Holzmann J, Politi A, Nagasaka K, Hantsche-Grininger M, Walther N, Koch B, et al.
Elife
. 2019 Jun;
8.
PMID: 31204999
The organisation of mammalian genomes into loops and topologically associating domains (TADs) contributes to chromatin structure, gene expression and recombination. TADs and many loops are formed by cohesin and positioned...
4.
Cai Y, Hossain M, Heriche J, Politi A, Walther N, Koch B, et al.
Nature
. 2018 Sep;
561(7723):411-415.
PMID: 30202089
Essential biological functions, such as mitosis, require tight coordination of hundreds of proteins in space and time. Localization, the timing of interactions and changes in cellular structure are all crucial...
5.
Ivanov M, Ladurner R, Poser I, Beveridge R, Rampler E, Hudecz O, et al.
EMBO J
. 2018 Jun;
37(15).
PMID: 29930102
Chromosome segregation depends on sister chromatid cohesion which is established by cohesin during DNA replication. Cohesive cohesin complexes become acetylated to prevent their precocious release by WAPL before cells have...
6.
Kurzbauer M, Pradillo M, Kerzendorfer C, Sims J, Ladurner R, Oliver C, et al.
Plant Cell
. 2018 Jan;
30(2):415-428.
PMID: 29352063
Fanconi anemia (FA) is a human autosomal recessive disorder characterized by chromosomal instability, developmental pathologies, predisposition to cancer, and reduced fertility. So far, 19 genes have been implicated in FA,...
7.
Ladurner R, Straight A
Cell
. 2016 Nov;
167(4):889-891.
PMID: 27814517
Kinetochores are complex multiprotein machines that link chromosomes to dynamic microtubules for chromosome segregation. Two studies in Cell reveal the structure of the human MIS12 and budding yeast MIND kinetochore...
8.
Davidson I, Goetz D, Zaczek M, Molodtsov M, Huis In t Veld P, Weissmann F, et al.
EMBO J
. 2016 Nov;
35(24):2671-2685.
PMID: 27799150
The spatial organization, correct expression, repair, and segregation of eukaryotic genomes depend on cohesin, ring-shaped protein complexes that are thought to function by entrapping DNA It has been proposed that...
9.
Ladurner R, Kreidl E, Ivanov M, Ekker H, Idarraga-Amado M, Busslinger G, et al.
EMBO J
. 2016 Feb;
35(6):635-53.
PMID: 26903600
Cohesion between sister chromatids is established during DNA replication but needs to be maintained to enable proper chromosome-spindle attachments in mitosis or meiosis. Cohesion is mediated by cohesin, but also...
10.
Huis In t Veld P, Herzog F, Ladurner R, Davidson I, Piric S, Kreidl E, et al.
Science
. 2014 Nov;
346(6212):968-72.
PMID: 25414306
Chromosome segregation depends on sister chromatid cohesion mediated by cohesin. The cohesin subunits Smc1, Smc3, and Scc1 form tripartite rings that are thought to open at distinct sites to allow...