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Jan-Bert van Klinken

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Articles 7
Citations 149
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Recent Articles
1.
Ferrer R, Jaspers Y, Dijkstra I, Breeuwsma N, van Klinken J, Romero C, et al.
J Inherit Metab Dis . 2024 Dec; 48(1):e12832. PMID: 39704488
X-linked adrenoleukodystrophy (ALD) is a peroxisomal disorder resulting from pathogenic variants in the ABCD1 gene that primarily affects the nervous system and is characterized by progressive axonal degeneration in the...
2.
Jaspers Y, Meyer S, Pras-Raves M, Dijkstra I, Wever E, Dane A, et al.
J Lipid Res . 2024 May; 65(6):100567. PMID: 38795862
Lipids play pivotal roles in an extensive range of metabolic and physiological processes. In recent years, the convergence of trapped ion mobility spectrometry and MS has enabled 4D-lipidomics, a highly...
3.
Lackner K, Sailer S, van Klinken J, Wever E, Pras-Raves M, Dane A, et al.
Biochim Biophys Acta Mol Cell Biol Lipids . 2023 Jan; 1868(4):159285. PMID: 36690320
Alkylglycerol monooxygenase (AGMO) and plasmanylethanolamine desaturase (PEDS1) are enzymes involved in ether lipid metabolism. While AGMO degrades plasmanyl lipids by oxidative cleavage of the ether bond, PEDS1 exclusively synthesizes a...
4.
Nahon K, Janssen L, Sardjoe Mishre A, Bilsen M, van der Eijk J, Botani K, et al.
Diabetes Obes Metab . 2020 Jun; 22(11):2032-2044. PMID: 32558052
Aim: To compare the effects of cold exposure and the β3-adrenergic receptor agonist mirabegron on plasma lipids, energy expenditure and brown adipose tissue (BAT) activity in South Asians versus Europids....
5.
Heemskerk M, van den Berg S, Pronk A, van Klinken J, Boon M, Havekes L, et al.
Am J Physiol Endocrinol Metab . 2014 Jan; 306(7):E808-13. PMID: 24473440
The lipid-lowering effect of niacin has been attributed to the inhibition of cAMP production in adipocytes, thereby inhibiting intracellular lipolysis and release of nonesterified fatty acids (NEFA) to the circulation....
6.
van den Berg S, Heemskerk M, Geerling J, van Klinken J, Schaap F, Bijland S, et al.
FASEB J . 2013 May; 27(8):3354-62. PMID: 23650188
Mutations in apolipoprotein A5 (APOA5) have been associated with hypertriglyceridemia in humans and mice. This has been attributed to a stimulating role for APOA5 in lipoprotein lipase-mediated triglyceride hydrolysis and...
7.
Coomans C, van den Berg S, Houben T, van Klinken J, van den Berg R, Pronk A, et al.
FASEB J . 2013 Jan; 27(4):1721-32. PMID: 23303208
Circadian rhythm disturbances are observed in, e.g., aging and neurodegenerative diseases and are associated with an increased incidence of obesity and diabetes. We subjected male C57Bl/6J mice to constant light...