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James R Prudent

Explore the profile of James R Prudent including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 429
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Recent Articles
1.
Muller M, Grabnitz F, Barandun N, Shen Y, Wendt F, Steiner S, et al.
Nat Commun . 2021 Dec; 12(1):7036. PMID: 34857745
The molecular nanoscale organization of the surfaceome is a fundamental regulator of cellular signaling in health and disease. Technologies for mapping the spatial relationships of cell surface receptors and their...
2.
Jang S, Yu X, Montemayor-Garcia C, Ahmed K, Weinlander E, Lloyd R, et al.
Oncotarget . 2017 Feb; 8(15):24457-24468. PMID: 28160550
Background: EDC1 is a novel type of antibody-drug conjugate which binds and inhibits the Na,K-ATPase on the surface of cancer cells expressing dysadherin. The purpose of this study was to...
3.
Marshall D, Harried S, Murphy J, Hall C, Shekhani M, Pain C, et al.
Mol Ther . 2016 Jul; 24(10):1760-1770. PMID: 27434591
The human Na/K-ATPase (NKA) is a plasma membrane ion pump that uses ATP to help maintain the resting potential of all human cells. Inhibition of the NKA leads to cell...
4.
Sweeny L, Hartman Y, Zinn K, Prudent J, Marshall D, Shekhani M, et al.
Oral Oncol . 2013 Aug; 49(10):991-7. PMID: 23920309
Objectives: Despite advances in treatment modalities, head and neck squamous cell carcinoma (HNSCC) remains a challenge to treat with poor survival and high morbidity, necessitating a therapy with greater efficacy....
5.
Marshall D, Reisdorf E, Harms G, Beaty E, Moser M, Lee W, et al.
J Clin Microbiol . 2007 Oct; 45(12):3875-82. PMID: 17928425
There are numerous viral and bacterial causes of respiratory disease. To enable rapid and sensitive detection of even the most prevalent causes, there is a need for more-simplified testing systems...
6.
Nolte F, Marshall D, Rasberry C, Schievelbein S, Banks G, Storch G, et al.
J Clin Microbiol . 2007 Jun; 45(9):2779-86. PMID: 17596361
The MultiCode-PLx system (EraGen Biosciences, Inc., Madison, WI) for the detection of respiratory viruses uses an expanded genetic alphabet, multiplex PCR chemistry, and microsphere flow cytometry to rapidly detect and...
7.
Lee W, Grindle K, Pappas T, Marshall D, Moser M, Beaty E, et al.
J Clin Microbiol . 2007 Jun; 45(8):2626-34. PMID: 17537928
Human respiratory viruses are a diverse group of pathogens composed of hundreds of virus strains, and this presents a major challenge for diagnostic laboratories. To efficiently detect numerous viruses in...
8.
Svarovskaia E, Moser M, Bae A, Prudent J, Miller M, Borroto-Esoda K
J Clin Microbiol . 2006 Sep; 44(11):4237-41. PMID: 17005757
We report a real-time PCR assay capable of detecting drug-resistant human immunodeficiency virus type 1 reverse transcriptase K65R mutant virus at a level of 0.5% in polymorphic patient plasma specimens....
9.
Biggins J, Prudent J, Marshall D, Thorson J
Methods Mol Biol . 2006 Jun; 335:83-92. PMID: 16785622
Exploring the properties of molecules that cleave DNA (i.e., enzymatic nucleases, chemical footprinting agents, and naturally occurring DNA cleaving antibiotics) has been an ongoing process with benefits extending toward both...
10.
Prudent J
Expert Rev Mol Diagn . 2006 Mar; 6(2):245-52. PMID: 16512783
DNA is the only chemistry that allows for molecular recognition on demand. Unlike any other molecular recognition chemistry, DNA enables the simple design and rapid synthesis of molecule sets that...