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James E Gern

Explore the profile of James E Gern including associated specialties, affiliations and a list of published articles. Areas
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Articles 371
Citations 13570
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Recent Articles
1.
Miller R, Schuh H, Chandran A, Habre R, Angal J, Aris I, et al.
J Allergy Clin Immunol . 2025 Mar; PMID: 40089117
Background: Environmental exposures and social determinants likely influence specific childhood asthma phenotypes. Objective: We hypothesized that the Child Opportunity Index (COI) at birth, measuring multiple neighborhood opportunities, influences incidence rates...
2.
Thompson E, Zhong X, Carbonetto P, Morin A, Willwerscheid J, Visness C, et al.
medRxiv . 2025 Mar; PMID: 40034775
Background: Asthma is the most common chronic respiratory disease in children, but little is known about genetic contributions to its underlying endotypes. To address this gap, we studied the methylome,...
3.
Watkinson R, Bochkov Y, Gern J, Iosifidis T, Looi K, Laing I, et al.
Methods Mol Biol . 2025 Feb; 2903:113-139. PMID: 40016462
The nasal epithelium is the primary point of contact for inhaled respiratory viruses such as rhinovirus, respiratory syncytial virus, influenza, and coronavirus, among others. In order to establish infection, these...
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Gaberino C, Altman M, Gill M, Bacharier L, Gruchalla R, OConnor G, et al.
J Allergy Clin Immunol . 2025 Jan; PMID: 39788435
Background: Determining why some upper respiratory illnesses provoke asthma exacerbations remains an unmet need. Objective: We sought to identify transcriptome-wide gene expression changes associated with colds that progress to exacerbation....
6.
Lyall K, Dickerson A, Green A, Frndak S, Croen L, Ames J, et al.
Autism Res . 2025 Jan; PMID: 39778060
Prevalence of autism diagnosis has historically differed by demographic factors. Using data from 8224 participants drawn from the Environmental influences on Child Health Outcomes (ECHO) Program, we examined relationships between...
7.
Togias A, Gergen P, Liu A, Kim H, Wood R, OConnor G, et al.
J Allergy Clin Immunol . 2025 Jan; PMID: 39755282
Background: Rhinoconjunctivitis phenotypes are conventionally described on the basis of symptom severity, duration and seasonality, and aeroallergen sensitization. It is not known whether these phenotypes fully reflect the patterns of...
8.
Non A, Li X, Jones M, Oken E, Hartert T, Schoettler N, et al.
Am J Respir Crit Care Med . 2024 Dec; 211(3):464-476. PMID: 39642347
Race-based estimates of pulmonary function in children could influence the evaluation of asthma in children from racial and ethnic minoritized backgrounds. To determine if race-neutral (Global Lung Function Initiative [GLI]-Global)...
9.
Zelasko S, Swaney M, Sandstrom S, Lee K, Dixon J, Riley C, et al.
J Allergy Clin Immunol . 2024 Nov; 155(2):436-450. PMID: 39547283
Background: Microbial interactions mediating colonization resistance play key roles within the human microbiome, shaping susceptibility to infection from birth. The role of the nasal and oral microbiome in the context...
10.
Swaney M, Steidl O, Tackett A, Fye S, Lee K, Ong I, et al.
bioRxiv . 2024 Oct; PMID: 39464075
Prenatal and early life farm exposure, and breastfeeding, are associated with protection from allergic diseases. We hypothesize that farm exposure influences the human breast milk microbiome and immune proteins. The...