Jacquie L Harper
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Explore the profile of Jacquie L Harper including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Kodar K, McConnell M, Harper J, Timmer M, Stocker B
Immunol Cell Biol
. 2020 Mar;
98(5):411-422.
PMID: 32181513
Trehalose dibehenate (TDB), a ligand for the macrophage-inducible C-type lectin, has shown promise as an adjuvant for preventative vaccines and also as an anticancer agent in murine assays. The potential...
2.
Wahi K, Kodar K, McConnell M, Harper J, Timmer M, Stocker B
Inflammation
. 2019 Feb;
42(3):1129-1136.
PMID: 30806957
The tumour microenvironment predominantly consists of macrophages with phenotypes ranging from pro-inflammatory (M1-like) to anti-inflammatory (M2-like). Trehalose-6,6'-dibehenate (TDB) displays moderate anti-tumour activity and stimulates M1-like macrophages via the macrophage inducible...
3.
Stocker B, Kodar K, Wahi K, Foster A, Harper J, Mori D, et al.
Glycoconj J
. 2019 Jan;
36(1):69-78.
PMID: 30617946
Trehalose glycolipids (TGLs) are promising vaccine adjuvants, however effects of glycolipid presentation in the in vitro evaluation, and ultimate selection, of lead vaccine adjuvants are often overlooked. To this end,...
4.
Baey C, Yang J, Ronchese F, Harper J
PLoS One
. 2018 Nov;
13(11):e0206827.
PMID: 30383838
Hyperuricaemia is associated with various metabolic dysfunctions including obesity, type 2 diabetes mellitus, hypertension and in general metabolic syndrome, which are all associated with increased risk of cancer. However, the...
5.
Hall C, Sanderson L, Lawrence L, Pool B, van der Kroef M, Ashimbayeva E, et al.
J Clin Invest
. 2018 Mar;
128(5):1752-1771.
PMID: 29584621
Gout is the most common inflammatory arthritis affecting men. Acute gouty inflammation is triggered by monosodium urate (MSU) crystal deposition in and around joints that activates macrophages into a proinflammatory...
6.
Kodar K, Harper J, McConnell M, Timmer M, Stocker B
Immun Inflamm Dis
. 2017 Jul;
5(4):503-514.
PMID: 28722316
Introduction: Macrophages play a significant role in the progression of diseases, such as cancer, making them a target for immune-modulating agents. Trehalose dibehenate (TDB) is known to activate M1-like macrophages...
7.
Shaw O, Nyanhanda T, McGhie T, Harper J, Hurst R
Mol Nutr Food Res
. 2017 Apr;
61(9).
PMID: 28393456
CCL11, a chemokine, is linked to the early development of airways eosinophilia in allergic asthma. Therefore, CCL11 production is a target for abrogating eosinophilic-driven airway inflammation. Blackcurrants are high in...
8.
Marlini M, Mabuchi A, Mallard B, Hairulhisyam N, Akashi-Takamura S, Harper J, et al.
Exp Physiol
. 2016 Sep;
101(12):1492-1505.
PMID: 27634415
What is the central question of this study? The liver regenerative process is complex and involves a sequence of signalling events, but the possible involvement of structural and haemodynamic changes...
9.
Shaw O, Hurst R, Harper J
Am J Physiol Lung Cell Mol Physiol
. 2016 Jul;
311(3):L628-38.
PMID: 27371734
Lung fibrosis negatively impacts on lung function in chronic asthma and is linked to the development of profibrotic macrophage phenotypes. Epidemiological studies have found that lung function benefits from increased...
10.
Brooks C, Van Dalen C, Zacharasiewicz A, Simpson J, Harper J, Le Gros G, et al.
Respirology
. 2015 Dec;
21(3):460-6.
PMID: 26693952
Background And Objective: Neutrophilic inflammation has been implicated in non-eosinophilic asthma (NEA) in adults, but little is known about NEA in children/adolescents. We assessed clinical and inflammatory characteristics of NEA...