Jacqueline C Shultz
Overview
Explore the profile of Jacqueline C Shultz including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
285
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Shapiro B, Vu N, Shultz M, Shultz J, Mietla J, Gouda M, et al.
J Biol Chem
. 2016 Aug;
291(41):21669-21681.
PMID: 27519412
Melanoma differentiation-associated gene 7 (MDA-7/IL-24) exhibits cytotoxic effects on tumor cells while sparing untransformed cells, and Bcl-x(L) is reported to efficiently block the induction of cell death by MDA-7/IL-24. The...
2.
Barbour S, Nguyen P, Park M, Emani B, Lei X, Kambalapalli M, et al.
J Biol Chem
. 2015 Mar;
290(17):11021-31.
PMID: 25762722
Diabetes is a consequence of reduced β-cell function and mass, due to β-cell apoptosis. Endoplasmic reticulum (ER) stress is induced during β-cell apoptosis due to various stimuli, and our work...
3.
Vu N, Park M, Shultz J, Goehe R, Hoeferlin L, Shultz M, et al.
J Biol Chem
. 2013 Feb;
288(12):8575-8584.
PMID: 23396972
Caspase-9 has two splice variants, pro-apoptotic caspase-9a and anti-apoptotic caspase-9b, which are regulated by RNA trans-factors associated with exon 3 of caspase-9 pre-mRNA (C9/E3). In this study, we identified hnRNP...
4.
Shultz J, Vu N, Shultz M, Mba M, Shapiro B, Chalfant C
Mol Cancer Res
. 2012 Apr;
10(5):660-9.
PMID: 22522453
Two splice variants derived from the Bcl-x gene via alternative 5' splice site selection (5'SS) are proapoptotic Bcl-x(s) and antiapoptotic Bcl-x(L). Previously, our laboratory showed that apoptotic signaling pathways regulated...
5.
Shultz J, Chalfant C
J Clin Invest
. 2011 Dec;
122(1):16-9.
PMID: 22201677
Chronic inflammation has long been appreciated to play a critical role in tumor development and maintenance. Among the mechanisms involved in coordinating the initiation and resolution of inflammation are those...
6.
Shultz J, Goehe R, Murudkar C, Wijesinghe D, Mayton E, Massiello A, et al.
Mol Cancer Res
. 2011 May;
9(7):889-900.
PMID: 21622622
Increasing evidence points to the functional importance of alternative splice variations in cancer pathophysiology with the alternative pre-mRNA processing of caspase 9 as one example. In this study, we delve...
7.
Shultz J, Chalfant C
Expert Rev Anticancer Ther
. 2011 Apr;
11(4):499-502.
PMID: 21504315
No abstract available.
8.
Shultz J, Goehe R, Wijesinghe D, Murudkar C, Hawkins A, Shay J, et al.
Cancer Res
. 2010 Nov;
70(22):9185-96.
PMID: 21045158
Increasing evidence points to the functional importance of alternative splice variations in cancer pathophysiology. Two splice variants are derived from the CASP9 gene via the inclusion (Casp9a) or exclusion (Casp9b)...
9.
Goehe R, Shultz J, Murudkar C, Usanovic S, Lamour N, Massey D, et al.
J Clin Invest
. 2010 Oct;
120(11):3923-39.
PMID: 20972334
Caspase-9 is involved in the intrinsic apoptotic pathway and suggested to play a role as a tumor suppressor. Little is known about the mechanisms governing caspase-9 expression, but post-transcriptional pre-mRNA...
10.
Shultz J, Chalfant C
Chem Biol
. 2007 Dec;
14(12):1313-4.
PMID: 18096499
Interference with the alternative splicing of apoptotic factors offers an innovative and specific mechanism to target malignant cells. In this issue of Chemistry & Biology, Zhou et al. report on...