Ngoc T Vu
Overview
Explore the profile of Ngoc T Vu including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
138
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Recent Articles
1.
Maus K, Stephenson D, Macknight H, Vu N, Hoeferlin L, Kim M, et al.
Sci Signal
. 2023 Jul;
16(793):eadd6527.
PMID: 37433004
Uncontrolled inflammation is linked to poor outcomes in sepsis and wound healing, both of which proceed through distinct inflammatory and resolution phases. Eicosanoids are a class of bioactive lipids that...
2.
Vu N, Kim M, Stephenson D, Macknight H, Chalfant C
Mol Cancer Res
. 2022 May;
20(9):1429-1442.
PMID: 35560154
Implications: Our findings depict how CERK inhibition may serve as a new key point in combination therapeutic strategy for NSCLC, specifically precision therapeutics targeting NSCLC possessing a KRAS mutation.
3.
Kim M, Vu N, Wang X, Bulut G, Wang M, Uram-Tuculescu C, et al.
Mol Cancer Res
. 2022 Apr;
20(8):1284-1294.
PMID: 35412615
Implications: Our findings show that C9b can directly activate NF-κB pathway in vivo to modulate lung inflammation, immune cell influx, and peripheral immune responses, which demonstrates that C9b is key...
4.
Hirano Y, Gao Y, Stephenson D, Vu N, Malinina L, Simanshu D, et al.
Elife
. 2021 Nov;
10.
PMID: 34843431
No abstract available.
5.
Hirano Y, Gao Y, Simanshu D, Stephenson D, Vu N, Malinina L, et al.
Bio Protoc
. 2021 Mar;
11(3):e3906.
PMID: 33732793
Previous expression/purification strategies for cytosolic phospholipase Aα C2-domain in have relied on refolded protein recovered from inclusion bodies and sometimes containing C-terminal Cys139Ala and Cys141Ser substitutions to eliminate potential refolding...
6.
Hirano Y, Gao Y, Stephenson D, Vu N, Malinina L, Simanshu D, et al.
Elife
. 2019 May;
8.
PMID: 31050338
Ca-stimulated translocation of cytosolic phospholipase Aα (cPLAα) to the Golgi induces arachidonic acid production, the rate-limiting step in pro-inflammatory eicosanoid synthesis. Structural insights into the cPLAα preference for phosphatidylcholine (PC)-enriched...
7.
Shapiro B, Vu N, Shultz M, Shultz J, Mietla J, Gouda M, et al.
J Biol Chem
. 2016 Aug;
291(41):21669-21681.
PMID: 27519412
Melanoma differentiation-associated gene 7 (MDA-7/IL-24) exhibits cytotoxic effects on tumor cells while sparing untransformed cells, and Bcl-x(L) is reported to efficiently block the induction of cell death by MDA-7/IL-24. The...
8.
Vu N, Park M, Shultz M, Bulut G, Ladd A, Chalfant C
Cancer Res
. 2016 May;
76(10):2977-89.
PMID: 27197231
Alternate RNA processing of caspase-9 generates the splice variants caspase 9a (C9a) and caspase 9b (C9b). C9b lacks a domain present in C9a, revealing a tumorigenic function that drives the...
9.
Johnson R, Vu N, Griffin B, Gentry A, Archer K, Chalfant C, et al.
J Biol Chem
. 2015 Aug;
290(42):25717-27.
PMID: 26304115
Triple negative breast cancer (TNBC) represents an anomalous subset of breast cancer with a greatly reduced (30%) 5-year survival rate. The enhanced mortality and morbidity of TNBC arises from the...
10.
Vu N, Park M, Shultz J, Goehe R, Hoeferlin L, Shultz M, et al.
J Biol Chem
. 2013 Feb;
288(12):8575-8584.
PMID: 23396972
Caspase-9 has two splice variants, pro-apoptotic caspase-9a and anti-apoptotic caspase-9b, which are regulated by RNA trans-factors associated with exon 3 of caspase-9 pre-mRNA (C9/E3). In this study, we identified hnRNP...