J Richard McIntosh
Overview
Explore the profile of J Richard McIntosh including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
82
Citations
3897
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Link F, Borges A, Karo O, Jungblut M, Muller T, Meyer-Natus E, et al.
Elife
. 2024 Apr;
12.
PMID: 38619530
Endocytosis is a common process observed in most eukaryotic cells, although its complexity varies among different organisms. In , the endocytic machinery is under special selective pressure because rapid membrane...
2.
Gergely Z, Jones M, Zhou B, Cash C, McIntosh J, Betterton M
Proc Natl Acad Sci U S A
. 2023 Sep;
120(39):e2306480120.
PMID: 37725645
Kinesin-5 motor proteins play essential roles during mitosis in most organisms. Their tetrameric structure and plus-end-directed motility allow them to bind to and move along antiparallel microtubules, thereby pushing spindle...
3.
Gudimchuk N, McIntosh J
Nat Rev Mol Cell Biol
. 2021 Aug;
22(12):777-795.
PMID: 34408299
Microtubule dynamics and their control are essential for the normal function and division of all eukaryotic cells. This plethora of functions is, in large part, supported by dynamic microtubule tips,...
4.
Ulyanov E, Vinogradov D, McIntosh J, Gudimchuk N
PLoS One
. 2021 Jun;
16(6):e0253684.
PMID: 34138967
[This corrects the article DOI: 10.1371/journal.pone.0247022.].
5.
McIntosh J
Semin Cell Dev Biol
. 2021 Mar;
117:118-126.
PMID: 33781672
Anaphase A is the motion of recently separated chromosomes to the spindle pole they face. It is accompanied by the shortening of kinetochore-attached microtubules. The requisite tubulin depolymerization may occur...
6.
Ulyanov E, Vinogradov D, McIntosh J, Gudimchuk N
PLoS One
. 2021 Feb;
16(2):e0247022.
PMID: 33577570
Electron cryo-microscopy (Cryo-EM) is a powerful method for visualizing biological objects with up to near-angstrom resolution. Instead of chemical fixation, the method relies on very rapid freezing to immobilize the...
7.
Gudimchuk N, Ulyanov E, OToole E, Page C, Vinogradov D, Morgan G, et al.
Nat Commun
. 2020 Jul;
11(1):3765.
PMID: 32724196
Microtubules are dynamic tubulin polymers responsible for many cellular processes, including the capture and segregation of chromosomes during mitosis. In contrast to textbook models of tubulin self-assembly, we have recently...
8.
Edelmaier C, Lamson A, Gergely Z, Ansari S, Blackwell R, McIntosh J, et al.
Elife
. 2020 Feb;
9.
PMID: 32053104
The essential functions required for mitotic spindle assembly and chromosome biorientation and segregation are not fully understood, despite extensive study. To illuminate the combinations of ingredients most important to align...
9.
McIntosh J, OToole E, Page C, Morgan G
Methods Mol Biol
. 2019 Dec;
2101:191-209.
PMID: 31879906
Microtubules can be detected in light microscopes, but the limited resolution of these instruments means that the polymers appear as lines whose width is defined by the diffraction of light....
10.
OToole E, Morphew M, McIntosh J
Mol Biol Cell
. 2019 Dec;
31(3):184-195.
PMID: 31825721
Metaphase spindles exert pole-directed forces on still-connected sister kinetochores. The spindle must counter these forces with extensive forces to prevent spindle collapse. In small spindles, kinetochore microtubules (KMTs) connect directly...