J Richard McIntosh
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Explore the profile of J Richard McIntosh including associated specialties, affiliations and a list of published articles.
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82
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Recent Articles
11.
Bloodgood R, Miller K, Fitzharris T, McIntosh J
J Morphol
. 2018 Oct;
143(1):77-105.
PMID: 30326674
The termite gut flagellates are of interest because of their unusual motile organelles, their ability to digest cellulose, and their symbiotic relationship with prokaryotes inhabiting the insect gut. This report...
12.
McIntosh J, OToole E, Morgan G, Austin J, Ulyanov E, Ataullakhanov F, et al.
J Cell Biol
. 2018 May;
217(8):2691-2708.
PMID: 29794031
We used electron tomography to examine microtubules (MTs) growing from pure tubulin in vitro as well as two classes of MTs growing in cells from six species. The tips of...
13.
Melloy P, Shen S, White E, McIntosh J, Rose M
J Cell Biol
. 2017 Oct;
216(11):3883.
PMID: 29079667
No abstract available.
14.
McIntosh J
Annu Rev Cell Dev Biol
. 2017 Oct;
33:1-22.
PMID: 28992437
During my graduate work with Keith Porter, I became fascinated by the mitotic spindle, an interest that has motivated much of my scientific work ever since. I began spindle studies...
15.
Blackwell R, Edelmaier C, Sweezy-Schindler O, Lamson A, Gergely Z, OToole E, et al.
Sci Adv
. 2017 Jan;
3(1):e1601603.
PMID: 28116355
Mitotic spindles use an elegant bipolar architecture to segregate duplicated chromosomes with high fidelity. Bipolar spindles form from a monopolar initial condition; this is the most fundamental construction problem that...
16.
McIntosh J, Morphew M, Giddings Jr T
Cold Spring Harb Protoc
. 2017 Jan;
2017(1).
PMID: 28049809
Electron microscopy (EM) can provide images of cells with a spatial resolution that significantly surpasses that available from light microscopy (LM), even with modern methods that give LM "super resolution."...
17.
Morphew M, Giddings Jr T, McIntosh J
Cold Spring Harb Protoc
. 2017 Jan;
2017(1).
PMID: 28049779
Fission yeast cells can be prepared for electron microscopy (EM) in the frozen-hydrated state. This eliminates the requirement for dehydration and heavy metal staining when preparing samples for EM. As...
18.
Morphew M, Giddings Jr T, McIntosh J
Cold Spring Harb Protoc
. 2017 Jan;
2017(1).
PMID: 28049778
Electron microscopy (EM) immunolocalization of antigens in fission yeast can be accomplished with cells processed by rapid freezing and freeze-substitution followed by embedding in acrylic or methacrylate resins. Microtome sections...
19.
Giddings Jr T, Morphew M, McIntosh J
Cold Spring Harb Protoc
. 2017 Jan;
2017(1).
PMID: 28049777
Freezing samples while simultaneously subjecting them to a rapid increase in pressure, which inhibits ice crystal formation, is a reliable method for cryofixing fission yeast. The procedure consists simply of...
20.
McIntosh J, Hays T
Biology (Basel)
. 2016 Dec;
5(4).
PMID: 28009830
This chapter describes in summary form some of the most important research on chromosome segregation, from the discovery and naming of mitosis in the nineteenth century until around 1990. It...