J K Spitznagel
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Explore the profile of J K Spitznagel including associated specialties, affiliations and a list of published articles.
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Articles
117
Citations
2017
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Recent Articles
1.
Spitznagel J
Mol Biotechnol
. 1999 Feb;
10(3):237-45.
PMID: 9951703
That cationic proteins might be factors on the antimicrobial defenses of mammalian hosts and are apparently associated with the cytoplasmic granules of phagocytic leukocytes first became evident on the late...
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Roland K, Spitznagel J
Prog Clin Biol Res
. 1995 Jan;
392:3-14.
PMID: 8524935
Resistance to Polymyxin and CAP are conferred by a point mutation, pmrA505, in position 81 that results in an Arg to His substitution in pmrA, a regulator protein. The protein,...
4.
Roland K, Esther C, Spitznagel J
J Bacteriol
. 1994 Jun;
176(12):3589-97.
PMID: 8206837
We have isolated from Salmonella typhimurium a gene, designated pmrD, that confers resistance to the membrane-damaging drug, polymyxin B when expressed from the medium-copy-number plasmid pHSG576. The gene maps to...
5.
Roland K, Martin L, Esther C, Spitznagel J
J Bacteriol
. 1993 Jul;
175(13):4154-64.
PMID: 8391535
We isolated spontaneous mutations (pmrA) in the smooth strain Salmonella typhimurium LT2 that show increased resistance to the cationic antibacterial proteins of human neutrophils and to the drug polymyxin B....
6.
Pereira H, Erdem I, Pohl J, Spitznagel J
Proc Natl Acad Sci U S A
. 1993 May;
90(10):4733-7.
PMID: 8506327
CAP37 (cationic antimicrobial protein of molecular mass 37 kDa) is a multifunctional protein isolated from the granules of human neutrophils. It is antibiotic and chemotactic and binds lipopolysaccharide. A synthetic...
7.
Morgan J, Sukiennicki T, Pereira H, Spitznagel J, Guerra M, Larrick J
J Immunol
. 1991 Nov;
147(9):3210-4.
PMID: 1919011
Human cationic antimicrobial protein (CAP37) is a neutrophil granule protein with monocyte chemotactic and antibacterial activity. A CAP37 cDNA clone of 899 bp was isolated from an HL-60 cDNA library...
8.
Morgan J, Pereira H, Sukiennicki T, Spitznagel J, Larrick J
Adv Exp Med Biol
. 1991 Jan;
305:89-96.
PMID: 1755383
Cationic antimicrobial protein CAP37 (Mr = 37 kD) is derived from the azurophilic granules of human PMN. In vitro and in vivo studies demonstrate that CAP37 is a novel monocyte-specific...
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Pohl J, Pereira H, Martin N, Spitznagel J
FEBS Lett
. 1990 Oct;
272(1-2):200-4.
PMID: 2226832
We report the amino acid sequence of CAP37, a human neutrophil granule protein with antibacterial and monocyte-specific chemotactic activity. CAP37 is a single-chain protein consisting of 222 amino acid residues....