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J E Vivienne Watson

Explore the profile of J E Vivienne Watson including associated specialties, affiliations and a list of published articles. Areas
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Citations 213
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Recent Articles
1.
Magnusson M, Agnarsson B, Jonasson J, Tryggvason T, Aeffner F, le Roux L, et al.
Br J Cancer . 2023 Aug; 129(7):1142-1151. PMID: 37596405
Background: The TNM system is used to assess prognosis after colorectal cancer (CRC) diagnosis. Other prognostic factors reported include histopathological assessments of the tumour, tumour mutations and proteins in the...
2.
Gonzalez M, Lu D, Yousefi M, Kroll A, Lo C, Briseno C, et al.
J Exp Med . 2023 Mar; 220(6). PMID: 36995340
Phagocytosis is a key macrophage function, but how phagocytosis shapes tumor-associated macrophage (TAM) phenotypes and heterogeneity in solid tumors remains unclear. Here, we utilized both syngeneic and novel autochthonous lung...
3.
Rex K, Jeffries S, Brown M, Carlson T, Coxon A, Fajardo F, et al.
PLoS One . 2013 Jul; 8(7):e68328. PMID: 23861887
Sphingosine kinases (SPHKs) are enzymes that phosphorylate the lipid sphingosine, leading to the formation of sphingosine-1-phosphate (S1P). In addition to the well established role of extracellular S1P as a mitogen...
4.
Swearingen E, Fajardo F, Wang X, Watson J, Quon K, Kassner P
J Biomol Screen . 2010 Apr; 15(5):469-77. PMID: 20371867
Screening small interfering RNA (siRNA) libraries holds the potential to elucidate gene function as well as discover new targets for the therapeutic treatment of disease. Since the inception of siRNA...
5.
van Duin M, van Marion R, Vissers K, Watson J, van Weerden W, Schroder F, et al.
Genes Chromosomes Cancer . 2005 Sep; 44(4):438-49. PMID: 16130124
Copy number increase of 8q has previously been shown to be associated with a poor clinical outcome and tumor recurrence in patients with prostate cancer. In this study, a detailed...
6.
van Duin M, van Marion R, Watson J, Paris P, Lapuk A, Brown N, et al.
Cytometry A . 2004 Dec; 63(1):10-9. PMID: 15619731
Background: Array-based comparative genomic hybridization (aCGH) enables genome-wide quantitative delineation of genomic imbalances. A high-resolution contig array was developed specifically for chromosome 8q because this chromosome arm is frequently altered...
7.
Watson J, Kamkar S, James K, Kowbel D, Andaya A, Paris P, et al.
Prostate . 2004 Aug; 61(2):192-9. PMID: 15305342
Background: WFDC1/ps20 protein has been previously established as a growth suppressor of the prostate cancer cell line PC3. It maps to chromosome 16q23.1, a region of frequent loss of heterozygosity,...
8.
McAlhany S, Ayala G, Frolov A, Ressler S, Wheeler T, Watson J, et al.
Prostate . 2004 Aug; 61(2):182-91. PMID: 15305341
Background: WAP-type four disulfide core (WFDC1)/ps20 is a member of the whey acidic protein family, which includes several serine protease inhibitors. Expression of WFDC1/ps20 was previously demonstrated in the normal...
9.
Paris P, Andaya A, Fridlyand J, Jain A, Weinberg V, Kowbel D, et al.
Hum Mol Genet . 2004 May; 13(13):1303-13. PMID: 15138198
Prostate cancer is the most commonly diagnosed non-cutaneous neoplasm among American males and is the second leading cause of cancer-related death. Prostate specific antigen screening has resulted in earlier disease...
10.
Watson J, Doggett N, Albertson D, Andaya A, Chinnaiyan A, van Dekken H, et al.
Oncogene . 2004 Mar; 23(19):3487-94. PMID: 15007382
We have constructed a high-resolution genomic microarray of human chromosome 16q, and used it for comparative genomic hybridization analysis of 16 prostate tumors. We demarcated 10 regions of genomic loss...