Flordeliza Fajardo
Overview
Explore the profile of Flordeliza Fajardo including associated specialties, affiliations and a list of published articles.
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6
Citations
203
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Recent Articles
1.
Harper T, Sharma A, Kaliyaperumal S, Fajardo F, Hsu K, Liu L, et al.
Toxicol Sci
. 2022 May;
189(1):32-50.
PMID: 35583313
Bispecific T-cell engager (BiTE) molecules have great potential to treat cancer. Nevertheless, dependent on the targeted tumor antigen, the mechanism of action that drives efficacy may also contribute to on-target/off-tumor...
2.
Shen Y, Eng J, Fajardo F, Liang L, Li C, Collins P, et al.
J Immunother Cancer
. 2022 Mar;
10(3).
PMID: 35296559
Background: Bispecific T-cell engager (BiTE) molecules induce redirected lysis of cancer cells by T cells and are an emerging modality for solid tumor immunotherapy. While signs of clinical activity have...
3.
Zuch de Zafra C, Fajardo F, Zhong W, Bernett M, Muchhal U, Moore G, et al.
Clin Cancer Res
. 2019 Mar;
25(13):3921-3933.
PMID: 30918018
Purpose: Despite advances in the treatment of multiple myeloma, new therapies are needed to induce more profound clinical responses. T-cell-redirected lysis triggered by bispecific antibodies recruiting T cells to cancer...
4.
Rex K, Jeffries S, Brown M, Carlson T, Coxon A, Fajardo F, et al.
PLoS One
. 2013 Jul;
8(7):e68328.
PMID: 23861887
Sphingosine kinases (SPHKs) are enzymes that phosphorylate the lipid sphingosine, leading to the formation of sphingosine-1-phosphate (S1P). In addition to the well established role of extracellular S1P as a mitogen...
5.
Babij C, Zhang Y, Kurzeja R, Munzli A, Shehabeldin A, Fernando M, et al.
Cancer Res
. 2011 Jul;
71(17):5818-26.
PMID: 21742770
Despite the prevalence of KRAS mutations in human cancers, there remain no targeted therapies for treatment. The serine-threonine kinase STK33 has been proposed to be required for the survival of...
6.
Swearingen E, Fajardo F, Wang X, Watson J, Quon K, Kassner P
J Biomol Screen
. 2010 Apr;
15(5):469-77.
PMID: 20371867
Screening small interfering RNA (siRNA) libraries holds the potential to elucidate gene function as well as discover new targets for the therapeutic treatment of disease. Since the inception of siRNA...