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Ivan da Rocha Pitta

Explore the profile of Ivan da Rocha Pitta including associated specialties, affiliations and a list of published articles. Areas
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Articles 80
Citations 644
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Recent Articles
1.
Goncalves S, Galdino L, Lima M, da Silva Moura J, Viana D, da Rosa M, et al.
Curr Top Med Chem . 2024 Aug; 24(25):2224-2237. PMID: 39136505
Objective: In this study, we have synthesized 19 Thiazolidine (TZD) derivatives to investigate their potential anti-ZIKV effects. Methods: Nineteen thiazolidine derivatives were synthesized and evaluated for their cytotoxicity and antiviral...
2.
Kayser J, Petry F, Alijar Souza M, Santin Zanatta Schindler M, Vidor Morgan L, Zimmermann Prado Rodrigues G, et al.
Behav Pharmacol . 2024 Jul; 35(6):338-350. PMID: 39051900
Increasing evidence indicates that neuroinflammation, oxidative stress, and neurotrophic factors play a key role in the pathophysiology of major depressive disorder (MDD). In addition, the attenuation of inflammatory response has...
3.
da Silva S, da Silva Moura J, Branco Junior J, de Moraes Gomes P, de Paula S, Viana D, et al.
Curr Top Med Chem . 2024 Mar; 24(14):1264-1277. PMID: 38523516
Background: Inflammation is a series of complex defense-related reactions. The inflammation cascade produces various pro-inflammatory mediators. Unregulated production of these pro-inflammatory mediators can lead to a wide range of diseases,...
4.
de Almeida A, Dantas A, de Oliveira Goncalves M, Chene C, Jeljeli M, Chouzenoux S, et al.
Inflammopharmacology . 2023 Jul; 32(1):433-446. PMID: 37477795
Thiazolidinediones (TZD) are synthetic molecules that have a range of biological effects, including antifibrotic and anti-inflammatory, and they may represent a promising therapeutic strategy for systemic sclerosis (SSc). The aim...
5.
Oliveira P, Cardoso P, de Paula Silva S, Duarte A, da Rosa M, Barreto de Melo Rego M, et al.
Clin Biochem . 2023 Mar; 116:11-15. PMID: 36858300
Background: Although immunostaining of galectins is associated with cartilage damage, the serum levels of these lectins in osteoarthritis (OA) are not fully understood. Objective: Therefore, we evaluate the concentrations of...
6.
Mariz H, Sato E, Cardoso P, Goncalves R, Duarte A, Barreto de Melo Rego M, et al.
Inflammation . 2022 Dec; 46(2):730-738. PMID: 36459355
Inflammatory T lymphocyte cytokines contribute to tissue damage in SLE patients. Vitamin D (Vit D) has a well-established immunomodulatory action, but few studies have addressed the effect of 1,25 dihydroxyvitamin...
7.
Emmanoella Sebulsqui Saraiva T, Zimmermann Prado Rodrigues G, Kayser J, Dallegrave E, Maus N, Veiverberg A, et al.
Toxicol Mech Methods . 2022 Apr; 32(9):705-715. PMID: 35410575
Schizophrenia is a psychiatric disorder that affects 1% of the world population and is treated with antipsychotics, which may induce important biochemical and hematological alterations. Since it is necessary to...
8.
de Freitas Ramalho E, Viana D, Costa V, Pitta M, Barreto de Melo Rego M, da Rocha Pitta I, et al.
Med Chem . 2022 Mar; 18(9):980-989. PMID: 35249500
Background: Oxazolidinones display several biological effects, including anticancer activity. The purpose of this present work was to investigate a series of novel oxazolidinone derivatives with potential antineoplastic activity. Their mechanisms...
9.
Brayner Cavalcanti M, Bezerra Leite L, Manoel de Queiroz D, de Salazar E Fernandes T, Mendes de Oliveira W, Pereira M, et al.
Int J Radiat Biol . 2021 Sep; 97(12):1649-1656. PMID: 34586957
Purpose: Patients submitted to radiotherapy (RT) may present in their healthy tissues surrounding the treated tumor, some typical acute inflammatory reactions induced by ionizing radiation (IR). The manifestation of inflammatory...
10.
Cardoso P, Lopes Marques C, de Melo Vilar K, Dantas A, Duarte A, da Rocha Pitta I, et al.
Autoimmune Dis . 2021 May; 2021:6672987. PMID: 34055402
Objectives: Rheumatoid arthritis affects about 1% of the world's population. This is a chronic autoimmune disease. It is predominant in females with progressive joint damage. Immune cells are involved, especially...