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Suely Lins Galdino

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Recent Articles
1.
Santin J, Daufenback Machado I, Rodrigues S, Teixeira S, Muscara M, Lins Galdino S, et al.
PLoS One . 2013 Oct; 8(10):e76894. PMID: 24124600
The present study aimed to show the in vivo mechanisms of action of an indole-thiazolidine molecule peroxisome-proliferator activated receptor pan-agonist (PPAR pan) and cyclooxygenase (COX) inhibitor, LYSO-7, in an ethanol/HCl-induced...
2.
da Silva J, Mariz H, da Rocha Jr L, Oliveira P, Dantas A, Duarte A, et al.
Clinics (Sao Paulo) . 2013 Jun; 68(6):766-71. PMID: 23778483
Objectives: Hydroxychloroquine is an antimalarial agent that has been used in systemic lupus erythematosus and rheumatoid arthritis treatment for many years. Recently, novel mechanisms of action have been proposed, thereby...
3.
Duarte A, Dantas A, de Ataide Mariz H, Dos Santos F, da Silva J, da Rocha Jr L, et al.
Mol Biol Rep . 2013 May; 40(8):4889-92. PMID: 23645091
The immunological role of interleukin 27 has been reported in various inflammatory diseases, but its importance in systemic lupus erythematosus pathogenesis is not completely established. The aim of this study...
4.
Oliveira P, Barreto de Melo Rego M, da Silva R, Brayner Cavalcanti M, Lins Galdino S, Correia M, et al.
Biomed Res Int . 2013 Apr; 2013:263968. PMID: 23586026
Cratylia mollis lectin has already established cytokine induction in Th1 and Th2 pathways. Thereby, this study aimed to evaluate Cramoll 1, 4 in IL-6, IL-17A, IL-22, and IL-23 induction as...
5.
Pitta M, da Rocha Pitta M, Barreto de Melo Rego M, Lins Galdino S
Mini Rev Med Chem . 2013 Feb; 13(4):493-508. PMID: 23373654
Schistosomiasis is a devastating worldwide widespread tropical disease that currently affects more than 230 million people, making it an issue of great socioeconomic and public health importance. Unfortunatelly there is...
6.
Dos Santos Gomes F, de Melo C, Peixoto C, de Lima M, Lins Galdino S, Alves Pereira V, et al.
Parasitol Res . 2012 Sep; 111(6):2361-6. PMID: 22941528
Imidazolidine derivatives are key components for the development of bioactive compounds for the treatment of many diseases, especially Chagas. In fact, others studies showed that the imidazolidine-2,4-dione has stood out...
7.
Silva A, Torres D, Wanessa Santos Rocha S, Dos Santos Gomes F, Santos Silva B, Donato M, et al.
Cardiovasc Pathol . 2012 Jul; 22(1):81-90. PMID: 22795892
Background: Atherosclerotic cardiovascular disease is a chronic inflammatory condition. Thiazolidinediones (TZDs) are used to enhance sensitivity to insulin and have demonstrated a protective effect over a variety of cardiovascular markers...
8.
da Silva A, de Andrade Lemoine Neves J, Irmao J, Costa V, Souza V, de Medeiros P, et al.
ScientificWorldJournal . 2012 May; 2012:520524. PMID: 22623908
Previous studies conducted with the imidazolidinic derivative 3-benzyl-5-(4-chloro-arylazo)-4-thioxo-imidazolidin-2-one (LPSF-PT05) show outstanding activity against adult Schistosoma mansoni worms in vitro. In the first phase of this study, S. mansoni-infected mice were...
9.
da Rocha Jr L, Duarte A, Dantas A, Mariz H, da Rocha Pitta I, Lins Galdino S, et al.
J Rheumatol . 2012 May; 39(7):1320-5. PMID: 22589261
Objective: To analyze the role of interleukin 22 (IL-22) in rheumatoid arthritis (RA). Methods: IL-22 serum levels were measured in 83 patients with established RA under treatment with disease-modifying antirheumatic...
10.
Barros F, Silva T, da Rocha Pitta M, Bezerra D, Costa-Lotufo L, de Moraes M, et al.
Bioorg Med Chem . 2012 May; 20(11):3533-9. PMID: 22546208
Although their exact role in controlling tumour growth and apoptosis in humans remains undefined, acridine and thiazolidine compounds have been shown to act as tumour suppressors in most cancers. Based...