Ivan da Rocha Pitta
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Explore the profile of Ivan da Rocha Pitta including associated specialties, affiliations and a list of published articles.
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80
Citations
644
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Recent Articles
11.
da Silva S, da Silva Moura J, de Sousa Nunes T, da Rocha Pitta I, da Rocha Pitta M
Curr Drug Targets
. 2021 Apr;
23(5):441-457.
PMID: 33858312
The quinolinic ring, present in several molecules, possesses a great diversity of biological activities. Therefore, this ring is in the structural composition of several candidates of drugs in preclinical and...
12.
Quirino M, Pereira M, de Souza M, da Rocha Pitta I, Filho A, Albuquerque M, et al.
Eur J Histochem
. 2021 Mar;
65(1).
PMID: 33666065
The sialic acid-binding immunoglobulin-type lectin Siglec-15 is a promising target to cancer immunotherapy in several tumor types. The present study aimed to investigate Siglec-15 expression in gastric cancer (GC) patient...
13.
Carvalho L, de Sena W, Abdelhay E, Pereira M, Pitta M, de Lima M, et al.
Naunyn Schmiedebergs Arch Pharmacol
. 2021 Jan;
394(6):1153-1166.
PMID: 33475759
The present study aimed to evaluate the mechanism of action of the antineoplastic activity of an oxazolidine derivative, LPSF/NB-3 (5-(4-cloro-benzilideno)-3-etil-2-tioxo-oxazolidin-4-ona). Cytotoxicity assays were performed in peripheral blood mononuclear cells (PBMCs)...
14.
Santos R, Constantino Cunha E, de Mello G, Rizzo J, Ferreira de Oliveira J, de Lima M, et al.
Med Chem
. 2020 Sep;
17(3):289-297.
PMID: 32914717
Background: Moderate to severe asthma could be induced by diverse proinflammatory cytokines, as IL-17 and IFN-γ, which are also related to treatment resistance and airway hyperresponsiveness. Oxazolidines emerged as a...
15.
Cavalcanti N, Melo Vilar K, Duarte A, Barreto de Melo Rego M, Pereira M, da Rocha Pitta I, et al.
Virus Res
. 2020 Jun;
286:198062.
PMID: 32565125
Chikungunya fever (CHIKF) is an arboviral disease that has caused an epidemic burst of chronic inflammatory joint disease in Latin America in the last few years. Efforts are being spent...
16.
de Almeida A, Dantas A, Pereira M, Barreto de Melo Rego M, Guimaraes Goncalves R, da Rocha Pitta I, et al.
Immunobiology
. 2020 Jun;
225(3):151964.
PMID: 32517886
Objective: The objective of the present study was to evaluate the serum levels of soluble oncostatin M (OSM), OSM receptor (sOSMR) and glycoprotein130 (sgp130) in patients with systemic sclerosis (SSc),...
17.
Oliveira P, da Paixao A, da Rocha Junior L, Duarte A, Pereira M, Barreto de Melo Rego M, et al.
Immunobiology
. 2020 Feb;
225(3):151908.
PMID: 32051095
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint damage, and it may present with comorbidities at the systemic level. The Th1/Th2/Th17 CD4 lymphocyte imbalance produces inflammatory...
18.
da Rocha Junior L, Duarte A, Barreto de Melo Rego M, de Almeida A, de Melo Vilar K, de Lima H, et al.
Immunol Lett
. 2020 Jan;
220:38-43.
PMID: 31954799
Background: Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic and progressive inflammation that can cause a high degree of disability in affected individuals. Proinflammatory cytokines play central...
19.
Silva O, Ribeiro-Filho H, Avelino T, Tittanegro T, Figueira A, Rabelo L, et al.
Clin Exp Pharmacol Physiol
. 2020 Jan;
47(5):798-808.
PMID: 31909493
The present investigation aimed to characterize the effect of a short-time treatment with a new thiazolidinedione (TZD) derivative, GQ-130, on metabolic alterations in rats fed a high-fat diet (HFD). We...
20.
Overexpression of UDP-Glucose 4-Epimerase Is Associated with Differentiation Grade of Gastric Cancer
de Souza M, Filho A, Albuquerque A, Quirino M, de Souza Albuquerque M, Cordeiro M, et al.
Dis Markers
. 2019 Dec;
2019:6325326.
PMID: 31827638
The UDP-glucose 4-epimerase (GALE) is a glycosyltransferase, which acts on protein and lipid glycosylation in normal and neoplastic cells. This study is aimed at investigating the differential tissue expression of...