Ismael Rodriguez-Espigares
Overview
Explore the profile of Ismael Rodriguez-Espigares including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
292
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Herrera L, Andreassen S, Caroli J, Rodriguez-Espigares I, Kermani A, Keseru G, et al.
Nucleic Acids Res
. 2024 Nov;
53(D1):D425-D435.
PMID: 39558158
G protein-coupled receptors (GPCRs) are membrane-spanning transducers mediating the actions of numerous physiological ligands and drugs. The GPCR database GPCRdb supports a large global research community with reference data, analysis,...
2.
Kapla J, Rodriguez-Espigares I, Ballante F, Selent J, Carlsson J
PLoS Comput Biol
. 2021 May;
17(5):e1008936.
PMID: 33983933
The determination of G protein-coupled receptor (GPCR) structures at atomic resolution has improved understanding of cellular signaling and will accelerate the development of new drug candidates. However, experimental structures still...
3.
Koklic T, Hrovat A, Guixa-Gonzalez R, Rodriguez-Espigares I, Navio D, Frangez R, et al.
Molecules
. 2021 Mar;
26(4).
PMID: 33673080
This study investigated the effect of type 1 gonadotropin releasing hormone receptor (GnRH-R) localization within lipid rafts on the properties of plasma membrane (PM) nanodomain structure. Confocal microscopy revealed colocalization...
4.
Rodriguez-Espigares I, Torrens-Fontanals M, Tiemann J, Aranda-Garcia D, Ramirez-Anguita J, Stepniewski T, et al.
Nat Methods
. 2020 Jul;
17(8):861-862.
PMID: 32704182
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
5.
Rodriguez-Espigares I, Torrens-Fontanals M, Tiemann J, Aranda-Garcia D, Ramirez-Anguita J, Stepniewski T, et al.
Nat Methods
. 2020 Jul;
17(8):777-787.
PMID: 32661425
G-protein-coupled receptors (GPCRs) are involved in numerous physiological processes and are the most frequent targets of approved drugs. The explosion in the number of new three-dimensional (3D) molecular structures of...
6.
Jaiteh M, Rodriguez-Espigares I, Selent J, Carlsson J
PLoS Comput Biol
. 2020 Mar;
16(3):e1007680.
PMID: 32168319
Rational drug design for G protein-coupled receptors (GPCRs) is limited by the small number of available atomic resolution structures. We assessed the use of homology modeling to predict the structures...
7.
Stepniewski T, Torrens-Fontanals M, Rodriguez-Espigares I, Giorgino T, Primdahl K, Vik A, et al.
Bioorg Med Chem
. 2018 Jun;
26(12):3580-3587.
PMID: 29866479
The oxoeicosanoid receptor 1 (OXER1) is a member of the G-protein coupled receptors (GPCR) family, and is involved in inflammatory processes and oncogenesis. As such it is an attractive target...
8.
Rodriguez-Espigares I, Kaczor A, Stepniewski T, Selent J
Methods Mol Biol
. 2017 Dec;
1705:321-334.
PMID: 29188569
The observation of biased agonism in G protein-coupled receptors (GPCRs) has provided new approaches for the development of more efficacious and safer drugs. However, in order to rationally design biased...
9.
Ramirez-Anguita J, Rodriguez-Espigares I, Guixa-Gonzalez R, Bruno A, Torrens-Fontanals M, Varela-Rial A, et al.
Biotechnol Appl Biochem
. 2017 Sep;
65(1):29-37.
PMID: 28877377
The serotonin 5-hydroxytryptamine 2A (5-HT ) receptor is a G-protein-coupled receptor (GPCR) relevant for the treatment of CNS disorders. In this regard, neuronal membrane composition in the brain plays a...
10.
Guixa-Gonzalez R, Albasanz J, Rodriguez-Espigares I, Pastor M, Sanz F, Marti-Solano M, et al.
Nat Commun
. 2017 Feb;
8:14505.
PMID: 28220900
Cholesterol is a key component of cell membranes with a proven modulatory role on the function and ligand-binding properties of G-protein-coupled receptors (GPCRs). Crystal structures of prototypical GPCRs such as...