Idit Hazan
Overview
Explore the profile of Idit Hazan including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
324
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0
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Recent Articles
1.
Lubin R, Patel A, Mackerodt J, Zhang Y, Gvili R, Mulder K, et al.
J Exp Med
. 2024 Oct;
221(11).
PMID: 39417994
Dendritic cells (DC) are specialized mononuclear phagocytes that link innate and adaptive immunity. They comprise two principal subsets: plasmacytoid DC (pDC) and conventional DC (cDC). Understanding the generation, differentiation, and...
2.
Shiloh R, Lubin R, David O, Geron I, Okon E, Hazan I, et al.
Blood
. 2023 Sep;
142(20):1740-1751.
PMID: 37738562
Histiocytoses are inflammatory myeloid neoplasms often driven by somatic activating mutations in mitogen-activated protein kinase (MAPK) cascade genes. H syndrome is an inflammatory genetic disorder caused by germ line loss-of-function...
3.
Lubin R, Gvili R, Hazan I, Yona S
Curr Protoc
. 2023 Aug;
3(8):e873.
PMID: 37610279
Dendritic cells (DCs) enable the immune system to mount and modulate precisely targeted responses to various threats across the organism by bridging innate and adaptive immunity. Historically, DCs have been...
4.
Hazan I, Monin J, Bouwman B, Crosetto N, Aqeilan R
Cell Rep
. 2019 Oct;
29(3):560-572.e4.
PMID: 31618627
DNA double-strand breaks (DSBs) are deleterious and tumorigenic but could also be essential for DNA-based processes. Yet the landscape of physiological DSBs and their role and repair are still elusive....
5.
Hazan I, Hofmann T, Aqeilan R
PLoS Genet
. 2016 Dec;
12(12):e1006436.
PMID: 27977694
The role of common fragile sites (CFSs) in cancer remains controversial. Two main views dominate the discussion: one suggests that CFS loci are hotspots of genomic instability leading to inactivation...
6.
Hazan I, Abu-Odeh M, Hofmann T, Aqeilan R
Mol Cell Oncol
. 2016 Jun;
2(4):e1008288.
PMID: 27308504
Common fragile sites (CFSs) tend to break upon replication stress and have been suggested to be "hot spots" for genomic instability. Recent evidence, however, implies that in the wake of...
7.
Yoshida T, Landhuis E, Dose M, Hazan I, Zhang J, Naito T, et al.
Blood
. 2013 Sep;
122(18):3149-59.
PMID: 24002445
Ikaros is a critical regulator of lymphocyte development and homeostasis; thus, understanding its transcriptional regulation is important from both developmental and clinical perspectives. Using a mouse transgenic reporter approach, we...
8.
Hansen K, Hazan I, Shanker S, Watt S, Verhein-Hansen J, Bahler J, et al.
PLoS Genet
. 2011 Jan;
7(1):e1001268.
PMID: 21253571
Nucleosomes in heterochromatic regions bear histone modifications that distinguish them from euchromatic nucleosomes. Among those, histone H3 lysine 9 methylation (H3K9me) and hypoacetylation have been evolutionarily conserved and are found...
9.
Yoshida T, Hazan I, Zhang J, Ng S, Naito T, Snippert H, et al.
Genes Dev
. 2008 May;
22(9):1174-89.
PMID: 18451107
The ability of somatic stem cells to self-renew and differentiate into downstream lineages is dependent on specialized chromatin environments that keep stem cell-specific genes active and key differentiation factors repressed...
10.
Wang A, Lane S, Tian Z, Sharon A, Hazan I, Liu H
Eukaryot Cell
. 2006 Dec;
6(2):253-61.
PMID: 17172437
The human fungal pathogen Candida albicans can undergo a morphological transition from a unicellular yeast growth form to a multicellular hyphal growth form. During hyphal growth, cell division is asymmetric....