Ida Alexandersson
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Explore the profile of Ida Alexandersson including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
172
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Recent Articles
1.
Uhrbom M, Muhl L, Genove G, Liu J, Palmgren H, Alexandersson I, et al.
Nat Commun
. 2024 Sep;
15(1):7643.
PMID: 39223126
Cell identities are defined by intrinsic transcriptional networks and spatio-temporal environmental factors. Here, we explored multiple factors that contribute to the identity of adipose stem cells, including anatomic location, microvascular...
2.
Ma H, Sukonina V, Zhang W, Meng F, Subhash S, Palmgren H, et al.
J Biol Chem
. 2023 May;
299(6):104795.
PMID: 37150320
In recent years, lactate has been recognized as an important circulating energy substrate rather than only a dead-end metabolic waste product generated during glucose oxidation at low levels of oxygen....
3.
Kroon T, Hagstedt T, Alexandersson I, Ferm A, Petersson M, Maurer S, et al.
Sci Transl Med
. 2022 Oct;
14(668):eabh1316.
PMID: 36288279
Circadian rhythms play a critical role in regulating metabolism, including daily cycles of feeding/fasting. Glucokinase (GCK) is central for whole-body glucose homeostasis and oscillates according to a circadian clock. GCK...
4.
Bonnet L, Alexandersson I, Baboota R, Kroon T, Oscarsson J, Smith U, et al.
Front Endocrinol (Lausanne)
. 2022 Sep;
13:957616.
PMID: 36072934
Cellular senescence is a state of irreversible cell cycle arrest and has been shown to play a key role in many diseases, including metabolic diseases. To investigate the potential contribution...
5.
Li Q, Hagberg C, Silva Cascales H, Lang S, Hyvonen M, Salehzadeh F, et al.
Nat Med
. 2021 Oct;
27(11):1941-1953.
PMID: 34608330
Obesity is considered an important factor for many chronic diseases, including diabetes, cardiovascular disease and cancer. The expansion of adipose tissue in obesity is due to an increase in both...
6.
Kroon T, Harms M, Maurer S, Bonnet L, Alexandersson I, Lindblom A, et al.
Mol Metab
. 2020 Apr;
36:100964.
PMID: 32248079
Objective: Peroxisome proliferator-activated receptors (PPARs) are key transcription factors that regulate adipose development and function, and the conversion of white into brown-like adipocytes. Here we investigated whether PPARα and PPARγ...
7.
Alexandersson I, Harms M, Boucher J
J Vis Exp
. 2020 Mar;
(156).
PMID: 32116300
White adipose tissue (WAT) dysregulation plays a central role in development of insulin resistance and type 2 diabetes (T2D). To develop new treatments for T2D, more physiologically relevant in vitro...
8.
Harms M, Li Q, Lee S, Zhang C, Kull B, Hallen S, et al.
Cell Rep
. 2019 Apr;
27(1):213-225.e5.
PMID: 30943403
White adipose tissue (WAT) is a central factor in the development of type 2 diabetes, but there is a paucity of translational models to study mature adipocytes. We describe a...