Hye Young Cho
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Explore the profile of Hye Young Cho including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
159
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Recent Articles
1.
Lee H, Lee J, Jang H, Cho H, Kang M, Bae S, et al.
Eur J Med Chem
. 2023 Nov;
263:115929.
PMID: 37956552
Targeted protein degradation (TPD) technology, such as proteolysis-targeting chimera (PROTAC), has become a new therapeutic modality. However, the degradation of undruggable proteins, such as those involved in protein-protein interactions (PPIs),...
2.
Kim D, Choi Y, Lee Y, Lim S, Kong J, Song J, et al.
Nat Commun
. 2022 May;
13(1):2572.
PMID: 35546148
Recent development of the chemical inhibitors specific to oncogenic KRAS (Kirsten Rat Sarcoma 2 Viral Oncogene Homolog) mutants revives much interest to control KRAS-driven cancers. Here, we report that AIMP2-DX2,...
3.
Lee S, Kwon N, Seo B, Lee J, Cho H, Kim K, et al.
Eur J Med Chem
. 2021 Apr;
218:113405.
PMID: 33831781
Recently, non-canonical roles of Lysyl-tRNA Synthetase (KRS), which is associated with cell migration and cancer metastasis, have been reported. Therefore, KRS has emerged as a promising target for the treatment...
4.
Chang P, Kim E, Jang W, Cho H, Choi Y
J Am Dent Assoc
. 2020 Dec;
152(3):234-239.
PMID: 33293029
Background And Overview: Orthodontic miniscrews have become popular tools for providing temporary anchorage during orthodontic treatment. Although they are easy to insert, damage to the periodontal ligament or dental root...
5.
Cho H, Jha R, Mushtaq A, Oh S, Jeon Y
Biochem Biophys Res Commun
. 2020 May;
527(3):831-838.
PMID: 32448505
p53 is the most studied tumor suppressor and a key transcriptional factor, with discrete domains that regulate cellular pathways such as apoptosis, angiogenesis, cell-cycle arrest, DNA repair, and senescence. Previous...
6.
Lim S, Cho H, Kim D, Roh Y, Son S, Mushtaq A, et al.
Nat Chem Biol
. 2019 Dec;
16(1):31-41.
PMID: 31792442
A tumorigenic factor, AIMP2 lacking exon 2 (AIMP2-DX2), is often upregulated in many cancers. However, how its cellular level is determined is not understood. Here, we report heat-shock protein HSP70...
7.
Jha R, Cho H, Mushtaq A, Lee K, Kim D, Kim S, et al.
Data Brief
. 2017 Apr;
11:533-536.
PMID: 28367482
AIMP2-DX2 is a splicing variant of AIMP2 protein which has been implicated in human lung cancer and chemoresistance of ovarian cancer (J.W. Choi, D.G. Kim, A.E. Lee, H.R. Kim, J.Y....
8.
Jha R, Cho H, Mushtaq A, Lee K, Kim D, Kim S, et al.
Protein Expr Purif
. 2017 Feb;
132:131-137.
PMID: 28185908
Besides their primary role in protein synthesis, aminoacyl-tRNA synthetases (AARSs) are involved in several non-canonical processes such as apoptosis, inflammation and angiogenesis through their interactions with various cellular proteins. Nine...
9.
Cho H, Kim S, Jeon Y
Methods
. 2016 Nov;
113:56-63.
PMID: 27789335
Lysyl-tRNA synthetase (KRS) is an enzyme that conjugates lysine to its cognate tRNAs in the process of protein synthesis. In addition to its catalytic function, KRS binds to the 67-kDa...
10.
Lee P, Yu S, Chang H, Cho H, Kang M, Chae B
Sci Rep
. 2016 Oct;
6:36088.
PMID: 27779222
Spherical black carbon aggregates were frequently observed in dust dry deposition in Daejeon, Korea. They were tens of micrometers in diameter and presented a mixture of black carbon and several...