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Hoa Quynh Do

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Articles 10
Citations 63
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Recent Articles
1.
Do H, Pirayesh E, Ferreira G, Pandhare A, Gallardo Z, Jansen M
Biophys J . 2024 Apr; 123(14):2185-2198. PMID: 38678367
Bupropion is an atypical antidepressant and smoking cessation drug that causes adverse effects such as insomnia, irritability, and anxiety. Bupropion inhibits dopamine and norepinephrine reuptake transporters and eukaryotic cation-conducting pentameric...
2.
Pirayesh E, Do H, Ferreira G, Pandhare A, Gallardo Z, Jansen M
bioRxiv . 2023 Oct; PMID: 37873398
Bupropion is an atypical antidepressant and smoking cessation drug which causes adverse effects such as insomnia, irritability, and anxiety. Bupropion inhibits dopamine and norepinephrine reuptake transporters and eukaryotic cation-conducting pentameric...
3.
Do H, Jansen M
J Gen Physiol . 2023 Apr; 155(6). PMID: 37026993
Serotonin or 5-hydroxytryptamine type 3 (5-HT3) receptors belong to the family of pentameric ligand-gated ion channels (pLGICs) that are therapeutic targets for psychiatric disorders and neurological diseases. Due to structural...
4.
Do H, Jansen M
Methods Mol Biol . 2022 Jun; 2507:425-444. PMID: 35773596
Proton coupled folate transporter (PCFT) is an integral membrane protein with 12 transmembrane segments localized to the plasma membrane. PCFT is the main route by which folate, vitamin B9, from...
5.
Do H, Bassil C, Andersen E, Jansen M
PLoS One . 2021 Nov; 16(11):e0253184. PMID: 34793461
The Proton-Coupled Folate Transporter (PCFT) is a transmembrane transport protein that controls the absorption of dietary folates in the small intestine. PCFT also mediates uptake of chemotherapeutically used antifolates into...
6.
Do H, Hewetson A, Borcik C, Hastert M, Whelly S, Wylie B, et al.
J Biol Chem . 2021 Jan; 296:100250. PMID: 33384380
Accumulating evidence shows that amyloids perform biological roles. We previously showed that an amyloid matrix composed of four members of the CRES subgroup of reproductive family 2 cystatins is a...
7.
Hewetson A, Khan N, Dominguez M, Do H, Kusko R, Borcik C, et al.
Proc Natl Acad Sci U S A . 2020 Jul; 117(28):16363-16372. PMID: 32601205
The epididymal lumen contains a complex cystatin-rich nonpathological amyloid matrix with putative roles in sperm maturation and sperm protection. Given our growing understanding for the biological function of this and...
8.
Do H, Hewetson A, Myers C, Khan N, Hastert M, Harsini F, et al.
Sci Rep . 2019 Jun; 9(1):9210. PMID: 31239483
An amyloid matrix composed of several family 2 cystatins, including the reproductive cystatin CRES, is an integral structure in the mouse epididymal lumen and has proposed functions in sperm maturation...
9.
Hewetson A, Do H, Myers C, Muthusubramanian A, Sutton R, Wylie B, et al.
Biomolecules . 2017 Jun; 7(3). PMID: 28661450
Amyloids are traditionally considered pathological protein aggregates that play causative roles in neurodegenerative disease, diabetes and prionopathies. However, increasing evidence indicates that in many biological systems nonpathological amyloids are formed...
10.
Ozkucur N, Monsees T, Perike S, Do H, Funk R
PLoS One . 2009 Jul; 4(7):e6131. PMID: 19584927
Background: Investigation of the mechanisms of guided cell migration can contribute to our understanding of many crucial biological processes, such as development and regeneration. Endogenous and exogenous direct current electric...