Roger Bryan Sutton
Overview
Explore the profile of Roger Bryan Sutton including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
159
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0
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Recent Articles
1.
Chiavarina B, Ronca R, Otaka Y, Sutton R, Rezzola S, Yokobori T, et al.
Oncogene
. 2022 Jan;
41(10):1410-1420.
PMID: 35031773
Cancer-associated fibroblasts (CAF) are important constituents of the tumor microenvironment (TME) and are major drivers of tumorigenesis. Yet, therapies aiming at eliminating CAF have failed to cure patients. This setback...
2.
Do H, Hewetson A, Borcik C, Hastert M, Whelly S, Wylie B, et al.
J Biol Chem
. 2021 Jan;
296:100250.
PMID: 33384380
Accumulating evidence shows that amyloids perform biological roles. We previously showed that an amyloid matrix composed of four members of the CRES subgroup of reproductive family 2 cystatins is a...
3.
Zhang X, Anthony B, Chai Z, Lee Dobbins A, Sutton R, Li C
Biomaterials
. 2020 Mar;
241:119906.
PMID: 32114218
The recombinant adeno-associated virus (rAAV) vector has been successfully employed in clinical trials for patients with blindness and bleeding diseases as well as neuromuscular disorders. To date, it remains a...
4.
Michalski N, Goutman J, Auclair S, de Monvel J, Tertrais M, Emptoz A, et al.
Elife
. 2017 Nov;
6.
PMID: 29111973
Hearing relies on rapid, temporally precise, and sustained neurotransmitter release at the ribbon synapses of sensory cells, the inner hair cells (IHCs). This process requires otoferlin, a six C-domain, Ca-binding...
5.
Guan Z, Bykhovskaia M, Jorquera R, Sutton R, Akbergenova Y, Littleton J
Elife
. 2017 Sep;
6.
PMID: 28895532
The synaptic vesicle Ca sensor Synaptotagmin binds Ca through its two C2 domains to trigger membrane interactions. Beyond membrane insertion by the C2 domains, other requirements for Synaptotagmin activity are...
6.
Hewetson A, Do H, Myers C, Muthusubramanian A, Sutton R, Wylie B, et al.
Biomolecules
. 2017 Jun;
7(3).
PMID: 28661450
Amyloids are traditionally considered pathological protein aggregates that play causative roles in neurodegenerative disease, diabetes and prionopathies. However, increasing evidence indicates that in many biological systems nonpathological amyloids are formed...
7.
OGrady G, Best H, Sztal T, Schartner V, Sanjuan-Vazquez M, Donkervoort S, et al.
Am J Hum Genet
. 2016 Oct;
99(5):1086-1105.
PMID: 27745833
This study establishes PYROXD1 variants as a cause of early-onset myopathy and uses biospecimens and cell lines, yeast, and zebrafish models to elucidate the fundamental role of PYROXD1 in skeletal...