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Hisatoshi Mimura

Explore the profile of Hisatoshi Mimura including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 461
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Recent Articles
1.
Kawai M, Oda H, Mimura H, Osaki T, Takeuchi S
HardwareX . 2024 Jul; 19:e00545. PMID: 39006472
The development of a compact and affordable fluorescence microscope can be a formidable challenge for growing needs in on-site testing and detection of fluorescent labeled biological systems, especially for those...
2.
Mimura H, Osaki T, Takamori S, Nakao K, Takeuchi S
Anal Chem . 2023 Nov; 95(47):17354-17361. PMID: 37968939
The measurement of ion permeation activity across planar lipid bilayers is a useful technique for the functional analysis and drug evaluation of ion channels at the single-molecule level. To enhance...
3.
Ogishi K, Osaki T, Mimura H, Hashimoto I, Morimoto Y, Miki N, et al.
Biosens Bioelectron . 2023 Jul; 237:115490. PMID: 37393766
This paper describes a novel signal processing method to characterize the activity of ion channels on a lipid bilayer system in a real-time and quantitative manner. Lipid bilayer systems, which...
4.
Yamada T, Sugiura H, Mimura H, Kamiya K, Osaki T, Takeuchi S
Sci Adv . 2021 Feb; 7(3). PMID: 33523876
This paper reports a volatile organic compound (VOC) sensor based on olfactory receptors that were reconstituted into a lipid bilayer and used in a specifically designed gas flow system for...
5.
Ito Y, Izawa Y, Osaki T, Kamiya K, Misawa N, Fujii S, et al.
Micromachines (Basel) . 2020 Dec; 11(12). PMID: 33352964
Lipid-bilayer devices have been studied for on-site sensors in the fields of diagnosis, food and environmental monitoring, and safety/security inspection. In this paper, we propose a lipid-bilayer-on-a-cup device for serial...
6.
Yamashita M, Kurokawa K, Sato Y, Yamagata A, Mimura H, Yoshikawa A, et al.
Nat Struct Mol Biol . 2010 Jan; 17(2):180-6. PMID: 20062059
The exocyst complex is a hetero-octameric protein complex that functions during cell polarization by tethering the secretory vesicle to the target membrane. The yeast exocyst subunit Sec3 binds to phosphatidylinositol...
7.
Yamagata A, Mimura H, Sato Y, Yamashita M, Yoshikawa A, Fukai S
Genes Cells . 2009 Dec; 15(1):29-41. PMID: 20015340
Tail anchored (TA) proteins, which are important for numerous cellular processes, are defined by a single transmembrane domain (TMD) near the C-terminus. The membrane insertion of TA proteins is mediated...
8.
Yoshikawa A, Sato Y, Yamashita M, Mimura H, Yamagata A, Fukai S
FEBS Lett . 2009 Sep; 583(20):3317-22. PMID: 19766637
NEMO is essential for activation of the NF-kappaB signaling pathway, which is regulated by ubiquitination of proteins. The C-terminal leucine zipper of NEMO and its adjacent coiled-coil region (CC2-LZ) reportedly...
9.
Sato Y, Yoshikawa A, Mimura H, Yamashita M, Yamagata A, Fukai S
EMBO J . 2009 Jun; 28(16):2461-8. PMID: 19536136
RAP80 has a key role in the recruitment of the Abraxas-BRCC36-BRCA1-BARD1 complex to DNA-damage foci for DNA repair through specific recognition of Lys 63-linked polyubiquitinated proteins by its tandem ubiquitin-interacting...
10.
Sato Y, Yoshikawa A, Yamagata A, Mimura H, Yamashita M, Ookata K, et al.
Nature . 2008 Sep; 455(7211):358-62. PMID: 18758443
Deubiquitinating enzymes (DUBs) remove ubiquitin from conjugated substrates to regulate various cellular processes. The Zn(2+)-dependent DUBs AMSH and AMSH-LP regulate receptor trafficking by specifically cleaving Lys 63-linked polyubiquitin chains from...