Atsushi Yamagata
Overview
Explore the profile of Atsushi Yamagata including associated specialties, affiliations and a list of published articles.
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Articles
49
Citations
1420
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Recent Articles
1.
Tehrani M, Matsuda I, Yamagata A, Kodama Y, Matsunaga T, Sato M, et al.
Nat Commun
. 2024 Aug;
15(1):7045.
PMID: 39147751
Arctic (E22G) mutation in amyloid-β (Aβ enhances Aβ40 fibril accumulation in Alzheimer's disease (AD). Unlike sporadic AD, familial AD (FAD) patients with the mutation exhibit more Aβ40 in the plaque...
2.
Yamagata A, Ito K, Suzuki T, Dohmae N, Terada T, Shirouzu M
Nat Commun
. 2024 Apr;
15(1):3027.
PMID: 38637505
More than one percent of people have epilepsy worldwide. Levetiracetam (LEV) is a successful new-generation antiepileptic drug (AED), and its derivative, brivaracetam (BRV), shows improved efficacy. Synaptic vesicle glycoprotein 2a...
3.
Ando S, Tanaka K, Matsumoto M, Oyama Y, Tomabechi Y, Yamagata A, et al.
J Biol Chem
. 2024 Apr;
300(5):107277.
PMID: 38588804
Protein phosphatase 2A (PP2A) is an essential serine/threonine protein phosphatase, and its dysfunction is involved in the onset of cancer and neurodegenerative disorders. PP2A functions as a trimeric holoenzyme whose...
4.
Bracun L, Yamagata A, Christianson B, Shirouzu M, Liu L
Structure
. 2023 Feb;
31(3):318-328.e3.
PMID: 36738736
In purple photosynthetic bacteria, the photochemical reaction center (RC) and light-harvesting complex 1 (LH1) assemble to form monomeric or dimeric RC-LH1 membrane complexes, essential for bacterial photosynthesis. Here, we report...
5.
Yamagata A, Murata Y, Namba K, Terada T, Fukai S, Shirouzu M
Nat Commun
. 2022 Nov;
13(1):7180.
PMID: 36424382
Calcareous soils cover one-third of all land and cause severe growth defects in plants due to the poor water solubility of iron at high pH. Poaceae species use a unique...
6.
Kikuchi A, Onoda H, Yamaguchi K, Kori S, Matsuzawa S, Chiba Y, et al.
Nat Commun
. 2022 Nov;
13(1):7130.
PMID: 36414620
DNMT1 is an essential enzyme that maintains genomic DNA methylation, and its function is regulated by mechanisms that are not yet fully understood. Here, we report the cryo-EM structure of...
7.
Cao P, Bracun L, Yamagata A, Christianson B, Negami T, Zou B, et al.
Nat Commun
. 2022 Apr;
13(1):1977.
PMID: 35418573
The reaction center (RC) and light-harvesting complex 1 (LH1) form a RC-LH1 core supercomplex that is vital for the primary reactions of photosynthesis in purple phototrophic bacteria. Some species possess...
8.
Katsumura S, Siddiqui N, Goldsmith M, Cheah J, Fujikawa T, Minegishi G, et al.
Cell Metab
. 2022 Apr;
34(4):564-580.e8.
PMID: 35385705
Hepatokines, secretory proteins from the liver, mediate inter-organ communication to maintain a metabolic balance between food intake and energy expenditure. However, molecular mechanisms by which hepatokine levels are rapidly adjusted...
9.
Yokoi N, Fukata Y, Okatsu K, Yamagata A, Liu Y, Sanbo M, et al.
Cell Rep
. 2021 Dec;
37(11):110107.
PMID: 34910912
What percentage of the protein function is required to prevent disease symptoms is a fundamental question in genetic disorders. Decreased transsynaptic LGI1-ADAM22 protein complexes, because of their mutations or autoantibodies,...
10.
Bracun L, Yamagata A, Christianson B, Terada T, Canniffe D, Shirouzu M, et al.
Sci Adv
. 2021 Jun;
7(25).
PMID: 34134992
The reaction center (RC)-light-harvesting complex 1 (LH1) supercomplex plays a pivotal role in bacterial photosynthesis. Many RC-LH1 complexes integrate an additional protein PufX that is key for bacterial growth and...