Toshihisa Osaki
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Explore the profile of Toshihisa Osaki including associated specialties, affiliations and a list of published articles.
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Articles
55
Citations
438
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Recent Articles
1.
Scott C, Porteus R, Takeuchi S, Osaki T, Lee S
Langmuir
. 2025 Jan;
41(4):2293-2299.
PMID: 39865883
Understanding the evolution of protocells, primitive compartments that distinguish self from nonself, is crucial for exploring the origin of life. Fatty acids and monoglycerides have been proposed as key components...
2.
Kawai M, Oda H, Mimura H, Osaki T, Takeuchi S
HardwareX
. 2024 Jul;
19:e00545.
PMID: 39006472
The development of a compact and affordable fluorescence microscope can be a formidable challenge for growing needs in on-site testing and detection of fluorescent labeled biological systems, especially for those...
3.
Mimura H, Osaki T, Takamori S, Nakao K, Takeuchi S
Anal Chem
. 2023 Nov;
95(47):17354-17361.
PMID: 37968939
The measurement of ion permeation activity across planar lipid bilayers is a useful technique for the functional analysis and drug evaluation of ion channels at the single-molecule level. To enhance...
4.
Ogishi K, Osaki T, Mimura H, Hashimoto I, Morimoto Y, Miki N, et al.
Biosens Bioelectron
. 2023 Jul;
237:115490.
PMID: 37393766
This paper describes a novel signal processing method to characterize the activity of ion channels on a lipid bilayer system in a real-time and quantitative manner. Lipid bilayer systems, which...
5.
Sugiyama H, Osaki T, Takeuchi S, Toyota T
Commun Chem
. 2023 Jan;
3(1):32.
PMID: 36703378
In investigations of the emergence of protocells at the origin of life, repeatable and continuous supply of molecules and ions into the closed lipid bilayer membrane (liposome) is one of...
6.
Kamiya K, Osaki T, Takeuchi S
RSC Adv
. 2022 May;
9(52):30071-30075.
PMID: 35530244
Lipid distribution in intracellular vesicles is different from that in the plasma membrane of eukaryotic cells. The lipid components in the intracellular vesicles are composed of phosphatidylserine and phosphatidylethanolamine in...
7.
Ogishi K, Osaki T, Morimoto Y, Takeuchi S
Lab Chip
. 2022 Feb;
22(5):890-898.
PMID: 35133381
This paper verifies the single-step and monolithic fabrication of 3D structural lipid bilayer devices using stereolithography. Lipid bilayer devices are utilized to host membrane proteins for biological assays or sensing...
8.
Sugiyama H, Osaki T, Takeuchi S, Toyota T
Langmuir
. 2021 Dec;
38(1):112-121.
PMID: 34967642
Liposomes, molecular self-assemblies resembling biological membranes, are a promising scaffold to investigate the physicochemical logic behind the complexity of living cells. Despite elaborate synthetic studies constructing cell-like chemical systems using...
9.
Hirata Y, Oda H, Osaki T, Takeuchi S
Lab Chip
. 2021 Jun;
21(14):2643-2657.
PMID: 34132291
Biohybrid odorant sensors that directly integrate a biological olfactory system have been increasingly studied and are suggested to be the next generation of ultrasensitive sensors by taking advantage of the...
10.
Maruyama Y, Sugawa M, Yamaguchi S, Davies T, Osaki T, Kobayashi T, et al.
Commun Biol
. 2021 Feb;
4(1):180.
PMID: 33568771
Centralspindlin, a complex of the MKLP1 kinesin-6 and CYK4 GAP subunits, plays key roles in metazoan cytokinesis. CYK4-binding to the long neck region of MKLP1 restricts the configuration of the...