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Hiroaki Aoyama

Explore the profile of Hiroaki Aoyama including associated specialties, affiliations and a list of published articles. Areas
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Articles 59
Citations 196
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Recent Articles
1.
Akane H, Toyoda T, Matsushita K, Uneyama M, Morikawa T, Kosaka T, et al.
Toxicol Pathol . 2025 Mar; :1926233251316880. PMID: 40079414
Although blood triiodothyronine (T3), thyroxine (T4), and thyroid-stimulating hormone (TSH) levels are useful for detecting antithyroid compounds in rodent toxicity studies, there are challenges with high variability due to sampling...
2.
Suto H, Ogata K, Minami K, Sato A, Tomiyama N, Kosaka T, et al.
J Toxicol Sci . 2024 Nov; 49(11):509-529. PMID: 39496387
We propose a modified Comparative Thyroid Assay (CTA, USEPA) utilizing a smaller number of Sprague-Dawley rats (N=10/group) that assesses brain thyroid hormone (TH) concentrations and periventricular heterotopia while maintaining assay...
3.
Ogata K, Suto H, Sato A, Maeda K, Minami K, Tomiyama N, et al.
J Toxicol Pathol . 2024 Oct; 37(4):173-187. PMID: 39359896
In a past study, we proposed a modified Comparative Thyroid Assay (CTA) with additional examinations of brain thyroid hormone (TH) concentrations and brain histopathology but with smaller group sizes. The...
4.
Katoh Y, Sato A, Takahashi N, Nishioka Y, Shimizu-Endo N, Ito T, et al.
Lab Invest . 2024 Sep; 104(10):102132. PMID: 39265891
Junctional epidermolysis bullosa is an intractable cutaneous disorder in humans causing skin fragility and blistering due to mutations in genes encoding essential molecules adhering epidermis and dermis including collagen XVII....
5.
Minami K, Sato A, Tomiyama N, Ogata K, Kosaka T, Hojo H, et al.
Curr Res Toxicol . 2024 May; 6:100168. PMID: 38693933
The Comparative Thyroid Assay (CTA, USEPA) is a screening test for thyroid hormone (TH) disruption in peripheral blood of dams and offspring. Recently, we began investigating feasible improvements to the...
6.
Akane H, Toyoda T, Matsushita K, Morikawa T, Kosaka T, Tajima H, et al.
J Appl Toxicol . 2024 Apr; 44(7):1084-1103. PMID: 38563354
Although measurements of blood triiodothyronine (T3), thyroxine (T4), and thyroid-stimulating hormone (TSH) levels in rodent toxicity studies are useful for detection of antithyroid substances, assays for these measurements are expensive...
7.
Wang T, Kaur L, Beniwal A, Furuhata Y, Aoyama H, Singh J
Plant Foods Hum Nutr . 2023 May; 78(2):375-382. PMID: 37199825
This study investigated the physico-chemical and textural properties of 3D-printed pea protein-only and pea protein-chicken-based hybrid meat analogs. Both pea protein isolate (PPI)-only and hybrid cooked meat analogs had a...
8.
Fujimoto S, Yaguchi H, Myosho T, Aoyama H, Sato Y, Kimura R
Sci Rep . 2022 Nov; 12(1):19989. PMID: 36411327
Cost-effective genotyping can be achieved by sequencing PCR amplicons. Short 3-10 base primers can arbitrarily amplify thousands of loci using only a few primers. To improve the sequencing efficiency of...
9.
Aoyama H, Yamagiwa K, Taira W, Kon T
PLoS One . 2022 Nov; 17(11):e0277560. PMID: 36383616
A unique historical architecture was created at Shuri Castle (Shuri-jo) in the Ryukyu Islands by its "Kawara" roof tiles. After the 13th and 14th centuries, Kawara tiles were introduced to...
10.
Minami K, Suto H, Sato A, Ogata K, Kosaka T, Hojo H, et al.
Regul Toxicol Pharmacol . 2022 Nov; 137:105283. PMID: 36372265
Concern has been raised that thyroid hormone disruptors (THDs) may potentially interfere with the developing brain, but effects of mild suppression of maternal THs by environmental contaminants on neonatal brain...