Hesso Farhan
Overview
Explore the profile of Hesso Farhan including associated specialties, affiliations and a list of published articles.
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79
Citations
2530
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Recent Articles
1.
Zahoor M, Dong Y, Preussner M, Reiterer V, Shameen Alam S, Haun M, et al.
EMBO J
. 2024 Aug;
43(19):4228-4247.
PMID: 39160274
Splicing and endoplasmic reticulum (ER)-proteostasis are two key processes that ultimately regulate the functional proteins that are produced by a cell. However, the extent to which these processes interact remains...
2.
Oberegger S, Misslinger M, Faserl K, Sarg B, Farhan H, Haas H
Open Biol
. 2024 Jun;
14(6):240033.
PMID: 38919062
is the predominant mould pathogen for humans. Adaption to host-imposed iron limitation has previously been demonstrated to be essential for its virulence. [2Fe-2S] clusters are crucial as cofactors of several...
3.
Heimdorfer D, Vorleuter A, Eschlbock A, Spathopoulou A, Suarez-Cubero M, Farhan H, et al.
Am J Hum Genet
. 2024 Jun;
111(7):1383-1404.
PMID: 38908375
The neurodevelopmental disorders Prader-Willi syndrome (PWS) and Schaaf-Yang syndrome (SYS) both arise from genomic alterations within human chromosome 15q11-q13. A deletion of the SNORD116 cluster, encoding small nucleolar RNAs, or...
4.
Mayer J, Boeck D, Werner M, Frankenhauser D, Geley S, Farhan H, et al.
Traffic
. 2024 Apr;
25(4):e12934.
PMID: 38613404
Alzheimer's disease (AD) pathology is characterized by amyloid beta (Aβ) plaques and dysfunctional autophagy. Aβ is generated by sequential proteolytic cleavage of amyloid precursor protein (APP), and the site of...
5.
Chevet E, De Matteis M, Eskelinen E, Farhan H
Traffic
. 2023 Aug;
24(11):546-548.
PMID: 37581229
TransitID is a new methodology based on proximity labeling allowing for the study of protein trafficking a the proteome scale.
6.
Phuyal S, Romani P, Dupont S, Farhan H
Trends Cell Biol
. 2023 May;
33(12):1049-1061.
PMID: 37236902
Mechanobiology studies the mechanisms by which cells sense and respond to physical forces, and the role of these forces in shaping cells and tissues themselves. Mechanosensing can occur at the...
7.
Ghannoum S, Fantini D, Zahoor M, Reiterer V, Phuyal S, Leoncio Netto W, et al.
PLoS Comput Biol
. 2023 Apr;
19(4):e1010995.
PMID: 37068117
Our understanding of how speed and persistence of cell migration affects the growth rate and size of tumors remains incomplete. To address this, we developed a mathematical model wherein cells...
8.
El-Gazzar A, Voraberger B, Rauch F, Mairhofer M, Schmidt K, Guillemyn B, et al.
EMBO Mol Med
. 2023 Mar;
15(4):e16834.
PMID: 36916446
Osteogenesis imperfecta (OI) is a genetically and clinically heterogeneous disorder characterized by bone fragility and reduced bone mass generally caused by defects in type I collagen structure or defects in...
9.
Chevet E, De Matteis M, Eskelinen E, Farhan H
Traffic
. 2023 Feb;
24(3):112-113.
PMID: 36849119
No abstract available.
10.
Phuyal S, Djaerff E, Le Roux A, Baker M, Fankhauser D, Mahdizadeh S, et al.
EMBO J
. 2022 Aug;
41(18):e110596.
PMID: 35938214
Cells are constantly exposed to various chemical and physical stimuli. While much has been learned about the biochemical factors that regulate secretory trafficking from the endoplasmic reticulum (ER), much less...