Santosh Phuyal
Overview
Explore the profile of Santosh Phuyal including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
571
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0
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Recent Articles
1.
Pfefferle A, Phuyal S, Netskar H, Malmberg K
EMBO J
. 2024 Jun;
43(13):2527-2529.
PMID: 38886578
No abstract available.
2.
Phuyal S, Romani P, Dupont S, Farhan H
Trends Cell Biol
. 2023 May;
33(12):1049-1061.
PMID: 37236902
Mechanobiology studies the mechanisms by which cells sense and respond to physical forces, and the role of these forces in shaping cells and tissues themselves. Mechanosensing can occur at the...
3.
Ghannoum S, Fantini D, Zahoor M, Reiterer V, Phuyal S, Leoncio Netto W, et al.
PLoS Comput Biol
. 2023 Apr;
19(4):e1010995.
PMID: 37068117
Our understanding of how speed and persistence of cell migration affects the growth rate and size of tumors remains incomplete. To address this, we developed a mathematical model wherein cells...
4.
Radulovic M, Wenzel E, Gilani S, Holland L, Lystad A, Phuyal S, et al.
EMBO J
. 2022 Nov;
41(24):e112677.
PMID: 36408828
Lysosome integrity is essential for cell viability, and lesions in lysosome membranes are repaired by the ESCRT machinery. Here, we describe an additional mechanism for lysosome repair that is activated...
5.
Phuyal S, Djaerff E, Le Roux A, Baker M, Fankhauser D, Mahdizadeh S, et al.
EMBO J
. 2022 Aug;
41(18):e110596.
PMID: 35938214
Cells are constantly exposed to various chemical and physical stimuli. While much has been learned about the biochemical factors that regulate secretory trafficking from the endoplasmic reticulum (ER), much less...
6.
Besse L, Besse A, Stolze S, Sobh A, Zaal E, van der Ham A, et al.
Cancer Res
. 2021 Jun;
81(17):4581-4593.
PMID: 34158378
The HIV-protease inhibitor nelfinavir has shown broad anticancer activity in various preclinical and clinical contexts. In patients with advanced, proteasome inhibitor (PI)-refractory multiple myeloma, nelfinavir-based therapy resulted in 65% partial...
7.
Alswady-Hoff M, Samulin Erdem J, Phuyal S, Knittelfelder O, Sharma A, Fonseca D, et al.
Int J Mol Sci
. 2021 Jun;
22(10).
PMID: 34069552
There is little in vitro data available on long-term effects of TiO exposure. Such data are important for improving the understanding of underlying mechanisms of adverse health effects of TiO....
8.
Phuyal S, Farhan H
J Cell Biol
. 2021 May;
220(6).
PMID: 33999114
Export from the ER is COPII-dependent. However, there is disagreement on the nature of the cargo-containing carriers that exit the ER. Two new studies from Shomron et al. (2021. J....
9.
Phuyal S, Baschieri F
Front Bioeng Biotechnol
. 2020 Nov;
8:597721.
PMID: 33195167
Mechanical stimuli have profound effects on the cellular architecture and functions. Over the past two decades, considerable progress has been made in unraveling the molecular machineries that confer cells the...
10.
Eck F, Phuyal S, Smith M, Kaulich M, Wilkinson S, Farhan H, et al.
J Cell Sci
. 2020 Aug;
133(18).
PMID: 32843575
While studies of the autophagy-related (ATG) genes in knockout models have led to an explosion of knowledge about the functions of autophagy components, the exact roles of LC3 and GABARAP...