Henning Birkedal-Hansen
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Explore the profile of Henning Birkedal-Hansen including associated specialties, affiliations and a list of published articles.
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1231
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Recent Articles
1.
Birkedal-Hansen H
J Periodontol
. 2018 Mar;
64 Suppl 5S:474-484.
PMID: 29539681
Matrix metalloproteinases (MMP) are a family of proteolytic enzymes that mediate the degradation of extracellular matrix macromolecules, including interstitial and basement membrane collagens, fibronectin, laminin, and proteoglycan core protein. The...
2.
Birkedal-Hansen H, Yamada S, Windsor J, Pollard A, Lyons G, Stetler-Stevenson W, et al.
Curr Protoc Cell Biol
. 2008 Sep;
Chapter 10:Unit 10.8.
PMID: 18819088
Matrix metalloproteinases are a class of enzymes that play an important role in the remodeling of the extracellular matrix in development and cancer metastasis. This unit describes a set of...
3.
Birkedal-Hansen H, Yamada S, Windsor J, Poulsen A, Lyons G, Stetler-Stevenson W, et al.
Curr Protoc Cell Biol
. 2008 Jan;
Chapter 10:Unit 10.8.
PMID: 18228416
Matrix metalloproteinases are a class of enzymes that play an important role in the remodeling of the extracellular matrix in development and cancer metastasis. This unit describes a set of...
4.
Filippov S, Koenig G, Chun T, Hotary K, Ota I, Bugge T, et al.
J Exp Med
. 2005 Sep;
202(5):663-71.
PMID: 16147977
During pathologic vessel remodeling, vascular smooth muscle cells (VSMCs) embedded within the collagen-rich matrix of the artery wall mobilize uncharacterized proteolytic systems to infiltrate the subendothelial space and generate neointimal...
5.
Szabova L, Yamada S, Birkedal-Hansen H, Holmbeck K
J Cell Physiol
. 2005 May;
205(1):123-32.
PMID: 15895410
Both mammary gland development and mammary carcinogenesis involve extensive remodeling of the mammary gland extracellular matrix. The expression of four membrane-type matrix metalloproteinases (MT-MMPs) with matrix remodeling potential in development...
6.
Lehti K, Allen E, Birkedal-Hansen H, Holmbeck K, Miyake Y, Chun T, et al.
Genes Dev
. 2005 Apr;
19(8):979-91.
PMID: 15805464
Platelet-derived growth factor (PDGF)/PDGFRbeta-dependent investment of the vascular endothelium by mural cells (i.e., pericytes and vascular smooth muscle cells; VSMCs) is critical for normal vessel wall structure and function. In...
7.
Atkinson J, Holmbeck K, Yamada S, Birkedal-Hansen H, Parks W, Senior R
Dev Dyn
. 2005 Mar;
232(4):1079-90.
PMID: 15739229
Matrix metalloproteinases (MMPs) are expressed during lung development, but their role may be limited, as mice deficient in MMP-3, 7, 9, or 12 develop a normal adult lung. Because membrane-type...
8.
Holmbeck K, Bianco P, Pidoux I, Inoue S, Billinghurst R, Wu W, et al.
J Cell Sci
. 2004 Dec;
118(Pt 1):147-56.
PMID: 15601659
The osteocyte is the terminally differentiated state of the osteogenic mesenchymal progenitor immobilized in the bone matrix. Despite their numerical prominence, little is known about osteocytes and their formation. Osteocytes...
9.
Sabeh F, Ota I, Holmbeck K, Birkedal-Hansen H, Soloway P, Balbin M, et al.
J Cell Biol
. 2004 Nov;
167(4):769-81.
PMID: 15557125
As cancer cells traverse collagen-rich extracellular matrix (ECM) barriers and intravasate, they adopt a fibroblast-like phenotype and engage undefined proteolytic cascades that mediate invasive activity. Herein, we find that fibroblasts...
10.
Chun T, Sabeh F, Ota I, Murphy H, McDonagh K, Holmbeck K, et al.
J Cell Biol
. 2004 Nov;
167(4):757-67.
PMID: 15545316
During angiogenesis, endothelial cells initiate a tissue-invasive program within an interstitial matrix comprised largely of type I collagen. Extracellular matrix-degradative enzymes, including the matrix metalloproteinases (MMPs) MMP-2 and MMP-9, are...