Heike Glauner
Overview
Explore the profile of Heike Glauner including associated specialties, affiliations and a list of published articles.
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7
Citations
85
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Recent Articles
1.
Witsenburg J, Glauner H, Muller J, Groenewoud J, Roth G, Bohmer F, et al.
PLoS One
. 2013 Nov;
8(10):e79277.
PMID: 24205378
T cell signaling is triggered through stimulation of the T cell receptor and costimulatory receptors. Receptor activation leads to the formation of membrane-proximal protein microclusters. These clusters undergo tyrosine phosphorylation...
2.
Ruttekolk I, Witsenburg J, Glauner H, Bovee-Geurts P, Ferro E, Verdurmen W, et al.
Mol Pharm
. 2012 Apr;
9(5):1077-86.
PMID: 22497602
With significant progress in delivery technologies, peptides and peptidomimetics are receiving increasing attention as potential therapeutics also for intracellular applications. However, analyses of the intracellular behavior of peptides are a...
3.
Ruttekolk I, Chakrabarti A, Richter M, Duchardt F, Glauner H, Verdurmen W, et al.
Mol Pharmacol
. 2011 Jan;
79(4):692-700.
PMID: 21247935
Here, we demonstrate that coupling to N-hydroxypropyl methacrylamide (HPMA) copolymer greatly enhances the activity of apoptosis-inducing peptides inside cells. Peptides corresponding to the BH3 domain of Bid were coupled to...
4.
Glauner H, Ruttekolk I, Hansen K, Steemers B, Chung Y, Becker F, et al.
Br J Pharmacol
. 2010 Jul;
160(4):958-70.
PMID: 20590591
Background And Purpose: In vitro assays that determine activities of drug candidates with isolated targets have only limited predictive value for activities in cellular assays. Poor membrane permeability and off-target...
5.
Hansen K, Ruttekolk I, Glauner H, Becker F, Brock R, Hannus S
Mol Immunol
. 2009 Aug;
46(16):3269-77.
PMID: 19699529
Antibodies of the IgG4 subclass, directed against cell surface antigens have received attention as therapeutic molecules due to their poor induction of the complement system. The MHC class II-directed IgG4...
6.
Fotin-Mleczek M, Henkler F, Hausser A, Glauner H, Samel D, Graness A, et al.
J Biol Chem
. 2003 Oct;
279(1):677-85.
PMID: 14557256
To investigate CD40 signaling complex formation in living cells, we used green fluorescent protein (GFP)-tagged CD40 signaling intermediates and confocal life imaging. The majority of cytoplasmic TRAF2-GFP and, to a...
7.
Glauner H, Siegmund D, Motejadded H, Scheurich P, Henkler F, Janssen O, et al.
Eur J Biochem
. 2002 Oct;
269(19):4819-29.
PMID: 12354113
To gain insight in the subcellular localization of tumor necrosis factor receptor-associated factor (TRAF4) we analyzed GFP chimeras of full-length TRAF4 and various deletion mutants derived thereof. While TRAF4-GFP (T4-GFP)...