Heidi Erlandsen
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Explore the profile of Heidi Erlandsen including associated specialties, affiliations and a list of published articles.
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30
Citations
681
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Recent Articles
1.
Skogvold A, Brakestad H, Erlandsen H, Leiros I
FEBS J
. 2025 Feb;
PMID: 40014458
The pyridoxal-5'-phosphate-dependent enzyme DoeD is a L-2,4-diaminobutyric acid (DABA) transaminase that is part of the degradation pathway of the compatible solute ectoine. Ectoines are used by halophilic organisms to maintain...
2.
Bregnard T, Bregnard T, Fairchild D, Chen X, Erlandsen H, Tarasov S, et al.
J Biol Chem
. 2025 Jan;
301(2):108149.
PMID: 39742997
Abnormalities in the expression of the ubiquitin ligase UBE3A (ubiquitin-protein ligase E3A)/E6AP (human papillomavirus E6-associated protein) are implicated in neurological disorders including Angelman syndrome and autism. Human UBE3A is expressed...
3.
Correia J, Stafford W, Erlandsen H, Cole J, Premathilaka S, Isailovic D, et al.
Biophys J
. 2024 Jun;
123(16):2506-2521.
PMID: 38898654
Covalent labeling of therapeutic drugs and proteins with polyethylene glycol (PEGylation) is an important modification for improving stability, solubility, and half-life. PEGylation alters protein solution behavior through its impact on...
4.
Bregnard T, Fairchild D, Erlandsen H, Semenova I, Szczepaniak R, Ahmed A, et al.
Structure
. 2023 Jul;
31(9):1086-1099.e6.
PMID: 37473756
The promyelocytic leukemia protein, PML, plays a vital role in the cellular response to oxidative stress; however, the molecular mechanism of its action remains poorly understood. Here, we identify redox-sensitive...
5.
McPherson K, Rizzo A, Erlandsen H, Chatterjee N, Walker G, Korzhnev D
J Biol Chem
. 2023 Jan;
299(2):102859.
PMID: 36592930
Translesion synthesis (TLS) DNA polymerase Polζ is crucial for the bypass replication over sites of DNA damage. The Rev7 subunit of Polζ is a HORMA (Hop1, Rev7, Mad2) protein that...
6.
Krucinska J, Lombardo M, Erlandsen H, Estrada A, Si D, Viswanathan K, et al.
Commun Biol
. 2022 May;
5(1):459.
PMID: 35562546
Two plasmid-encoded dihydrofolate reductase (DHFR) isoforms, DfrA1 and DfrA5, that give rise to high levels of resistance in Gram-negative bacteria were structurally and biochemically characterized to reveal the mechanism of...
7.
Erlandsen H, Jecrois A, Nichols J, Cole J, Royer Jr W
FEBS Lett
. 2022 Jan;
596(4):479-490.
PMID: 34997967
The activation of oncogenic C-terminal binding Protein (CtBP) transcriptional activity is coupled with NAD(H) binding and homo-oligomeric assembly, although the level of CtBP assembly and nucleotide binding affinity continues to...
8.
Krucinska J, Lombardo M, Erlandsen H, Hazeen A, Duay S, Pattis J, et al.
Sci Rep
. 2019 Nov;
9(1):17106.
PMID: 31745118
Many years ago, the natural secondary metabolite SF2312, produced by the actinomycete Micromonospora, was reported to display broad spectrum antibacterial properties against both Gram-positive and Gram-negative bacteria. Recent studies have...
9.
Mayo C, Erlandsen H, Mouser D, Feinstein A, Robinson V, May E, et al.
Biochemistry
. 2019 Jun;
58(27):2967-2977.
PMID: 31246429
The RNA-activated protein kinase, PKR, is a key mediator of the innate immunity response to viral infection. Viral double-stranded RNAs induce PKR dimerization and autophosphorylation. The PKR kinase domain forms...
10.
Maniaci B, Lipper C, Anipindi D, Erlandsen H, Cole J, Stec B, et al.
Biochemistry
. 2019 Apr;
58(17):2199-2207.
PMID: 30938154
The ability to precisely control protein complex formation has high utility in the expanding field of biomaterials. Driving protein-protein binding through metal-ligand bridging interactions is a promising method of achieving...