Harvey J Armbrecht
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Explore the profile of Harvey J Armbrecht including associated specialties, affiliations and a list of published articles.
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8
Citations
214
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Recent Articles
1.
Armbrecht H, Siddiqui A, Green M, Farr S, Kumar V, Banks W, et al.
J Alzheimers Dis
. 2015 Apr;
46(2):535-48.
PMID: 25854933
The senescence-accelerated mouse (SAMP8) strain exhibits an age-related decrease in memory accompanied by an increase in hippocampal amyloid-β protein precursor (AβPP) and amyloid-β peptide (Aβ). We have shown that administration...
2.
Chanakul A, Zhang M, Louw A, Armbrecht H, Miller W, Portale A, et al.
PLoS One
. 2013 Sep;
8(9):e72816.
PMID: 24019880
The mitochondrial enzyme 25-hydroxyvitamin D 1α-hydroxylase, which is encoded by the CYP27B1 gene, converts 25OHD to the biological active form of vitamin D, 1,25-dihydroxyvitamin D (1,25(OH)2D). Renal 1α-hydroxylase activity is...
3.
Armbrecht H, Siddiqui A, Green M, Farr S, Kumar V, Banks W, et al.
Neurobiol Aging
. 2013 Aug;
35(1):159-68.
PMID: 23969180
The senescence-accelerated mouse (SAMP8) strain exhibits decreased learning and memory and increased amyloid beta (Aβ) peptide accumulation at 12 months. To detect differences in gene expression in SAMP8 mice, we...
4.
Zhang M, Ranch D, Pereira R, Armbrecht H, Portale A, Perwad F
Endocrinology
. 2012 Feb;
153(4):1806-16.
PMID: 22334725
The X-linked hypophosphatemic (Hyp) mouse carries a loss-of-function mutation in the phex gene and is characterized by hypophosphatemia due to renal phosphate (Pi) wasting, inappropriately suppressed 1,25-dihydroxyvitamin D [1,25(OH)₂D] production,...
5.
Ritter C, Haughey B, Armbrecht H, Brown A
J Steroid Biochem Mol Biol
. 2012 Feb;
130(1-2):73-80.
PMID: 22326730
Parathyroid glands express the 25-hydroxyvitamin D(3) 1α-hydroxylase (1αOHase). 1,25-dihydroxyvitamin D(3) (calcitriol) synthesized by extrarenal tissues generally does not enter the circulation, but plays an autocrine/paracrine role specific to the cell...
6.
Morley J, Farr S, Kumar V, Armbrecht H
Curr Pharm Des
. 2012 Feb;
18(8):1123-30.
PMID: 22288401
The senescence accelerate mouse P8 (SAMP8) is an excellent model of early learning and memory problems. A number of studies have shown that it has cholinergic deficits, oxidative damage, alterations...
7.
Zhong Y, Armbrecht H, Christakos S
J Biol Chem
. 2009 Mar;
284(17):11059-69.
PMID: 19261615
Although parathyroid hormone (PTH) induces 25-hydroxyvitamin D(3) (25(OH)D(3)) 1alpha-hydroxylase (1alpha(OH)ase) under hypocalcemic conditions, previous studies showed that calcitonin, not PTH, has an important role in the maintenance of serum 1,25-dihydroxyvitamin...
8.
Armbrecht H, Lakshmi V, Wickstra J, Hsu F, Zenser T
Drug Metab Dispos
. 2007 Jan;
35(4):633-9.
PMID: 17251306
The incidence of colon cancer increases with age, and this may be related to altered metabolism and disposition of carcinogens. One such carcinogen implicated in colon cancer is the heterocyclic...