Hartmut Cuny
Overview
Explore the profile of Hartmut Cuny including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
22
Citations
711
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects
Bozon K, Cuny H, Sheng D, Martin E, Sipka A, Young P, et al.
Elife
. 2025 Mar;
13.
PMID: 40047807
Congenital malformations can originate from numerous genetic or non-genetic factors but in most cases the causes are unknown. Genetic disruption of nicotinamide adenine dinucleotide (NAD) de novo synthesis causes multiple...
2.
Szot J, Cuny H, Martin E, Sheng D, Iyer K, Portelli S, et al.
J Clin Invest
. 2024 Feb;
134(4).
PMID: 38357931
Nicotinamide adenine dinucleotide (NAD) is essential for embryonic development. To date, biallelic loss-of-function variants in 3 genes encoding nonredundant enzymes of the NAD de novo synthesis pathway - KYNU, HAAO,...
3.
Dunwoodie S, Bozon K, Szot J, Cuny H
Antioxid Redox Signal
. 2023 Jun;
39(16-18):1108-1132.
PMID: 37300479
Nicotinamide adenine dinucleotide (NAD) is an important molecule synthesized from tryptophan or vitamin B3 and involved in numerous cellular reactions. NAD deficiency during pregnancy causes congenital NAD deficiency disorder (CNDD)...
4.
Cuny H, Bozon K, Kirk R, Sheng D, Broer S, Dunwoodie S
Dis Model Mech
. 2022 Nov;
16(5).
PMID: 36374036
Nicotinamide adenine dinucleotide (NAD) is a key metabolite synthesised from vitamin B3 or tryptophan. Disruption of genes encoding NAD synthesis enzymes reduces NAD levels and causes congenital NAD deficiency disorder...
5.
Yang A, Alankarage D, Cuny H, Ip E, Almog M, Lu J, et al.
Circ Genom Precis Med
. 2022 May;
15(3):e003539.
PMID: 35522174
No abstract available.
6.
Cuny H, Kristianto E, Hodson M, Dunwoodie S
Anal Biochem
. 2021 Oct;
633:114409.
PMID: 34648806
Nicotinamide adenine dinucleotide (NAD) is a key metabolic intermediate found in all cells and involved in numerous cellular functions. Perturbances in the NAD metabolome are linked to various diseases such...
7.
Cuny H, Rapadas M, Gereis J, Martin E, Kirk R, Shi H, et al.
Proc Natl Acad Sci U S A
. 2020 Feb;
117(7):3738-3747.
PMID: 32015132
Causes for miscarriages and congenital malformations can be genetic, environmental, or a combination of both. Genetic variants, hypoxia, malnutrition, or other factors individually may not affect embryo development, however, they...
8.
Szot J, Campagnolo C, Cao Y, Iyer K, Cuny H, Drysdale T, et al.
Am J Hum Genet
. 2019 Dec;
106(1):129-136.
PMID: 31883644
Birth defects occur in up to 3% of all live births and are the leading cause of infant death. Here we present five individuals from four unrelated families, individuals who...
9.
Alankarage D, Ip E, Szot J, Munro J, Blue G, Harrison K, et al.
Genet Med
. 2018 Oct;
21(5):1111-1120.
PMID: 30293987
Purpose: Congenital heart disease (CHD) affects up to 1% of live births. However, a genetic diagnosis is not made in most cases. The purpose of this study was to assess...
10.
Szot J, Cuny H, Blue G, Humphreys D, Ip E, Harrison K, et al.
Circ Genom Precis Med
. 2018 Mar;
11(3):e001978.
PMID: 29555671
Background: Congenital heart disease (CHD)-structural abnormalities of the heart that arise during embryonic development-is the most common inborn malformation, affecting ≤1% of the population. However, currently, only a minority of...