Hans Zischka
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Explore the profile of Hans Zischka including associated specialties, affiliations and a list of published articles.
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107
Citations
3837
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Recent Articles
1.
Petruzzelli R, Catalano F, Crispino R, Polishchuk E, Elia M, Masone A, et al.
Nat Commun
. 2025 Feb;
16(1):1468.
PMID: 39922819
Copper (Cu) is a vitally important micronutrient, whose balance between essential and toxic levels requires a tightly regulated network of proteins. Dysfunction in key components of this network leads to...
2.
Michaelis V, Klemens L, Thiel A, Gremme A, Schwarz M, Kipp A, et al.
Chemosphere
. 2024 Dec;
370():143870.
PMID: 39638128
Environmental mercury (Hg) follows a biogeochemical cycle resulting in a variety of Hg species. Therefore, human exposure to the three Hg species inorganic Hg via crops and air, methyl Hg...
3.
Bialobrodzka E, Flis D, Akdogan B, Borkowska A, Wieckowski M, Antosiewicz J, et al.
Muscle Nerve
. 2024 Sep;
70(5):1111-1118.
PMID: 39225106
Introduction/aims: Swim training and regulation of copper metabolism result in clinical benefits in amyotrophic lateral sclerosis (ALS) mice. Therefore, the study aimed to determine whether swim training improves copper metabolism...
4.
Fontes A, Jauch A, Sailer J, Engler J, Azul A, Zischka H
Int J Mol Sci
. 2024 Jul;
25(14).
PMID: 39063122
Essential transition metals have key roles in oxygen transport, neurotransmitter synthesis, nucleic acid repair, cellular structure maintenance and stability, oxidative phosphorylation, and metabolism. The balance between metal deficiency and excess...
5.
Fontes A, Pierson H, Bierla J, Eberhagen C, Kinschel J, Akdogan B, et al.
Metabolism
. 2024 Jul;
158:155973.
PMID: 38986805
In Wilson disease (WD), liver copper (Cu) excess, caused by mutations in the ATPase Cu transporting beta (ATP7B), has been extensively studied. In contrast, in the gastrointestinal tract, responsible for...
6.
Heinze T, Ebert F, Ott C, Nagel J, Eberhagen C, Zischka H, et al.
Anal Bioanal Chem
. 2024 Jul;
416(20):4591-4604.
PMID: 38960940
From organs to subcellular organelles, trace element (TE) homeostasis is fundamental for many physiological processes. While often overlooked in early stages, manifested TE disbalance can have severe health consequences, particularly...
7.
Sailer J, Nagel J, Akdogan B, Jauch A, Engler J, Knolle P, et al.
Redox Biol
. 2024 Jul;
75:103256.
PMID: 38959622
Higher eukaryotes' life is impossible without copper redox activity and, literally, every breath we take biochemically demonstrates this. However, this dependence comes at a considerable price to ensure target-oriented copper...
8.
Hu Y, Mostert D, Orgler C, Andler O, Zischka H, Kazmaier U, et al.
Chembiochem
. 2024 May;
25(13):e202400024.
PMID: 38716781
Lagunamide A is a biologically active natural product with a yet unidentified molecular mode of action. Cellular studies revealed that lagunamide A is a potent inhibitor of cancer cell proliferation,...
9.
Maares M, Haupt A, Schussler C, Kulike-Koczula M, Hackler J, Keil C, et al.
Sci Rep
. 2024 Apr;
14(1):8859.
PMID: 38632369
No abstract available.
10.
Tsvilovskyy V, Ottenheijm R, Kriebs U, Schutz A, Diakopoulos K, Jha A, et al.
J Clin Invest
. 2024 Apr;
134(7).
PMID: 38557489
Regulated exocytosis is initiated by increased Ca2+ concentrations in close spatial proximity to secretory granules, which is effectively prevented when the cell is at rest. Here we showed that exocytosis...