Michaela Aichler
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Explore the profile of Michaela Aichler including associated specialties, affiliations and a list of published articles.
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102
Citations
6551
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Recent Articles
1.
Koch J, Schober S, Hindupur S, Schoning C, Klein F, Mantwill K, et al.
Nat Commun
. 2022 Aug;
13(1):4689.
PMID: 35948546
CDK4/6 inhibitors (CDK4/6i) and oncolytic viruses are promising therapeutic agents for the treatment of various cancers. As single agents, CDK4/6 inhibitors that are approved for the treatment of breast cancer...
2.
Zhao L, Chen F, Quitt O, Festag M, Ringelhan M, Wisskirchen K, et al.
Cell Microbiol
. 2021 Nov;
23(12):e13399.
PMID: 34729894
Hepatitis B virus (HBV) infection is a major health threat causing 880,000 deaths each year. Available therapies control viral replication but do not cure HBV, leaving patients at risk to...
3.
Kunzke T, Prade V, Buck A, Sun N, Feuchtinger A, Matzka M, et al.
Cancer Res
. 2021 Oct;
81(23):5862-5875.
PMID: 34666994
Asymptomatic anthracosis is the accumulation of black carbon particles in adult human lungs. It is a common occurrence, but the pathophysiologic significance of anthracosis is debatable. Using high mass resolution...
4.
Liu N, Gujrati V, Malekzadeh-Najafabadi J, Fuenzalida Werner J, Klemm U, Tang L, et al.
Photoacoustics
. 2021 May;
22:100263.
PMID: 33948433
Contrast enhancement in optoacoustic (photoacoustic) imaging can be achieved with agents that exhibit high absorption cross-sections, high photostability, low quantum yield, low toxicity, and preferential bio-distribution and clearance profiles. Based...
5.
Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples
Blutke A, Sun N, Xu Z, Buck A, Harrison L, Schriever S, et al.
Sci Rep
. 2020 Sep;
10(1):14461.
PMID: 32879402
Light sheet fluorescence microscopy (LSFM) of optically cleared biological samples represents a powerful tool to analyze the 3-dimensional morphology of tissues and organs. Multimodal combinations of LSFM with additional analyses...
6.
Fischer A, Koopmans T, Ramesh P, Christ S, Strunz M, Wannemacher J, et al.
Nat Commun
. 2020 Jun;
11(1):3068.
PMID: 32555155
Surgical adhesions are bands of scar tissues that abnormally conjoin organ surfaces. Adhesions are a major cause of post-operative and dialysis-related complications, yet their patho-mechanism remains elusive, and prevention agents...
7.
Niu Z, Sarkar R, Aichler M, Wester H, Yousefi B, Reif B
Chembiochem
. 2020 Apr;
21(17):2495-2502.
PMID: 32291951
Positron emission tomography (PET) tracer molecules like thioflavin T specifically recognize amyloid deposition in brain tissue by selective binding to hydrophobic or aromatic surface grooves on the β-sheet surface along...
8.
Kunzke T, Buck A, Prade V, Feuchtinger A, Prokopchuk O, Martignoni M, et al.
J Cachexia Sarcopenia Muscle
. 2020 Jan;
11(1):226-240.
PMID: 31965747
Background: Cachexia is the direct cause of at least 20% of cancer-associated deaths. Muscle wasting in skeletal muscle results in weakness, immobility, and death secondary to impaired respiratory muscle function....
9.
Lohofer F, Buchholz R, Glinzer A, Huber K, Haas H, Kaissis G, et al.
Sci Rep
. 2020 Jan;
10(1):79.
PMID: 31919465
Molecular imaging of atherosclerosis by Magnetic Resonance Imaging (MRI) has been impaired by a lack of validation of the specific substrate responsible for the molecular imaging signal. We therefore aimed...
10.
Correa-Gallegos D, Jiang D, Christ S, Ramesh P, Ye H, Wannemacher J, et al.
Nature
. 2019 Nov;
576(7786):287-292.
PMID: 31776510
Mammals form scars to quickly seal wounds and ensure survival by an incompletely understood mechanism. Here we show that skin scars originate from prefabricated matrix in the subcutaneous fascia. Fate...