H Llewelyn Roderick
Overview
Explore the profile of H Llewelyn Roderick including associated specialties, affiliations and a list of published articles.
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Articles
93
Citations
6422
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Recent Articles
1.
Tomar A, Ekhteraei-Tousi S, Roderick H
J Mol Cell Cardiol Plus
. 2025 Jan;
3():100029.
PMID: 39803359
No abstract available.
2.
Ronda O, Roderick H
J Mol Cell Cardiol Plus
. 2025 Jan;
10():100082.
PMID: 39801801
No abstract available.
3.
Cools J, Goovaerts B, Feyen E, Van den Bogaert S, Fu Y, Civati C, et al.
Nat Commun
. 2025 Jan;
16(1):576.
PMID: 39794341
Heart failure is a common and deadly disease requiring new treatments. The neuregulin-1/ERBB4 pathway offers cardioprotective benefits, but using recombinant neuregulin-1 as therapy has limitations due to the need for...
4.
Van Wauwe J, Mahy A, Craps S, Ekhteraei-Tousi S, Vrancaert P, Kemps H, et al.
Life Sci Alliance
. 2024 Sep;
7(12).
PMID: 39304345
PRDM16 is a transcription factor with histone methyltransferase activity expressed at the earliest stages of cardiac development. Pathogenic mutations in humans lead to cardiomyopathy, conduction abnormalities, and heart failure. PRDM16...
5.
Sasi A, Romaine A, Erusappan P, Melleby A, Hasic A, Dahl C, et al.
Matrix Biol Plus
. 2023 Dec;
19-20:100135.
PMID: 38076279
Cardiac fibrosis is a central pathological feature in several cardiac diseases, but the underlying molecular players are insufficiently understood. The extracellular matrix proteoglycan versican is elevated in heart failure and...
6.
Dries E, Gilbert G, Roderick H, Sipido K
Cell Calcium
. 2023 Jun;
114:102769.
PMID: 37390591
The ryanodine receptor type 2 (RyR) is a key player in Ca handling during excitation-contraction coupling. During each heartbeat, RyR channels are responsible for linking the action potential with the...
7.
Amoni M, Vermoortele D, Ekhteraei-Tousi S, Donate Puertas R, Gilbert G, Youness M, et al.
Circ Arrhythm Electrophysiol
. 2023 May;
16(5):e011677.
PMID: 37128895
Background: After myocardial infarction, the infarct border zone (BZ) is the dominant source of life-threatening arrhythmias, where fibrosis and abnormal repolarization create a substrate for reentry. We examined whether repolarization...
8.
Cools B, Nagaraju C, Vandendriessche K, Van Puyvelde J, Youness M, Roderick H, et al.
JACC Basic Transl Sci
. 2023 Apr;
8(3):301-315.
PMID: 37034286
In the sheep model with pathophysiologic changes similar to patients with repaired TOF, severe PR leads to fibrotic changes in the RV. Pulmonary valve replacement reverses these fibrotic changes. Early...
9.
Jin X, Meletiou A, Chung J, Tilunaite A, Demydenko K, Dries E, et al.
J Mol Cell Cardiol
. 2023 Apr;
179:47-59.
PMID: 37003353
Ca transients (CaT) underlying cardiomyocyte (CM) contraction require efficient Ca coupling between sarcolemmal Ca channels and sarcoplasmic reticulum (SR) ryanodine receptor Ca channels (RyR) for their generation; reduced coupling in...
10.
Leybaert L, De Smet M, Lissoni A, Allewaert R, Roderick H, Bultynck G, et al.
J Clin Invest
. 2023 Mar;
133(6).
PMID: 36919695
Connexins are crucial cardiac proteins that form hemichannels and gap junctions. Gap junctions are responsible for the propagation of electrical and chemical signals between myocardial cells and cells of the...