Stuart J Conway
Overview
Explore the profile of Stuart J Conway including associated specialties, affiliations and a list of published articles.
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90
Citations
1748
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Recent Articles
1.
Brennan P, Saunders R, Spanou M, Serafini M, Sun L, Heger G, et al.
bioRxiv
. 2024 Apr;
PMID: 38559242
Immunomodulatory imide drugs (IMiDs) including thalidomide, lenalidomide, and pomalidomide, can be used to induce degradation of a protein of interest that is fused to a short zinc finger (ZF) degron...
2.
Chao X, Johnson T, Temian M, Docker A, Wallabregue A, Scott A, et al.
J Am Chem Soc
. 2024 Feb;
146(7):4351-4356.
PMID: 38334376
Artificial ion transporters have been explored both as tools for studying fundamental ion transport processes and as potential therapeutics for cancer and channelopathies. Here we demonstrate that synthetic transporters may...
3.
4.
Schiedel M, McArdle D, Padalino G, Chan A, Forde-Thomas J, McDonough M, et al.
J Med Chem
. 2023 Dec;
66(23):15801-15822.
PMID: 38048437
Schistosomiasis is a disease affecting >200 million people worldwide, but its treatment relies on a single agent, praziquantel. To investigate new avenues for schistosomiasis control, we have conducted the first...
5.
Tosun C, Wallabregue A, Mallerman M, Phillips S, Edwards C, Conway S, et al.
JACS Au
. 2023 Nov;
3(11):3237-3246.
PMID: 38034969
Regions of hypoxia occur in most tumors and are a predictor of poor patient prognosis. Hypoxia-activated prodrugs (HAPs) provide an ideal strategy to target the aggressive, hypoxic, fraction of a...
6.
Russell C, Carter J, Borgia J, Bush J, Calderon F, Gabarro R, et al.
ACS Infect Dis
. 2023 Oct;
9(11):2340-2357.
PMID: 37906637
Leishmaniases are a collection of neglected tropical diseases caused by kinetoplastid parasites in the genus . Current chemotherapies are severely limited, and the need for new antileishmanials is of pressing...
7.
Thomas A, Serafini M, Grant E, Coombs E, Bluck J, Schiedel M, et al.
ACS Chem Biol
. 2023 Oct;
18(11):2405-2417.
PMID: 37874862
Target validation remains a challenge in drug discovery, which leads to a high attrition rate in the drug discovery process, particularly in Phase II clinical trials. Consequently, new approaches to...
8.
Booker S, Conway S, Lavasanifar A
ACS Bio Med Chem Au
. 2023 Apr;
1(1):1.
PMID: 37101979
No abstract available.
9.
Wallabregue A, Bolland H, Faulkner S, Hammond E, Conway S
J Am Chem Soc
. 2023 Jan;
145(4):2572-2583.
PMID: 36656915
Hypoxia (low oxygen levels) occurs in a range of biological contexts, including plants, bacterial biofilms, and solid tumors; it elicits responses from these biological systems that impact their survival. For...
10.
Aldrich C, Calderon F, Conway S, He C, Hooker J, Huryn D, et al.
ACS Chem Biol
. 2022 Oct;
17(10):2673-2678.
PMID: 36268572
No abstract available.