H Kotanides
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Explore the profile of H Kotanides including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
535
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Recent Articles
1.
Ludwig D, Kotanides H, Le T, Chavkin D, Bohlen P, Witte L
Gene
. 2001 May;
269(1-2):103-12.
PMID: 11376942
VDUP1 encodes a vitamin D3-inducible gene product that has been shown to be down-regulated in chemically-induced mammary tumors in rats. It has recently been reported to negatively regulate thioredoxin expression...
2.
Rousseau S, Houle F, Kotanides H, Witte L, Waltenberger J, Landry J, et al.
J Biol Chem
. 2000 Apr;
275(14):10661-72.
PMID: 10744763
In endothelial cells, vascular endothelial growth factor (VEGF) induces an accumulation of stress fibers associated with new actin polymerization and rapid formation of focal adhesions at the ventral surface of...
3.
Lu D, Kotanides H, Jimenez X, Zhou Q, Persaud K, Bohlen P, et al.
J Immunol Methods
. 1999 Dec;
230(1-2):159-71.
PMID: 10594363
Bispecific antibody (BsAb) technology has been successfully used as a means to construct novel antibody (Ab) molecules with increased avidity for binding, by combining two Ab or their fragments directed...
4.
Zhu Z, Lu D, Kotanides H, Santiago A, Jimenez X, Simcox T, et al.
Cancer Lett
. 1999 Jun;
136(2):203-13.
PMID: 10355750
The kinase insert domain-containing receptor (KDR) is the human vascular endothelial growth factor (VEGF) receptor responsible for the mitogenic and angiogenic effects of VEGF. There is much experimental evidence to...
5.
Witte L, Hicklin D, Zhu Z, Pytowski B, Kotanides H, Rockwell P, et al.
Cancer Metastasis Rev
. 1998 Oct;
17(2):155-61.
PMID: 9770111
Biological evidence suggests that interference with the function of the angiogenic growth factor receptor VEGFR2 (flk1/KDR) is a particularly promising strategy to inhibit tumor-induced angiogenesis. Proof of concept was established...
6.
Zhu Z, Rockwell P, Lu D, Kotanides H, Pytowski B, Hicklin D, et al.
Cancer Res
. 1998 Aug;
58(15):3209-14.
PMID: 9699643
A single-chain antibody phage display library was constructed from spleen cells of mice immunized with a soluble form of a human vascular endothelial growth factor (VEGF) receptor, kinase insert domain-containing...
7.
Kotanides H, Reich N
J Biol Chem
. 1996 Oct;
271(41):25555-61.
PMID: 8810328
This study addresses the function of STAT6 in interleukin-4-stimulated gene expression. A specific STAT6 DNA-binding target site has been identified in the promoter of the interleukin-4 receptor gene, and STAT6...
8.
Kotanides H, Moczygemba M, White M, Reich N
J Biol Chem
. 1995 Aug;
270(33):19481-6.
PMID: 7642632
The activation of a latent DNA binding factor by interleukin-4 (IL-4), the IL-4 nuclear activated factor (IL-4 NAF), occurs within minutes of IL-4 binding to its receptor. Molecular characterization of...
9.
Kotanides H, Reich N
Science
. 1993 Nov;
262(5137):1265-7.
PMID: 7694370
Interleukin-4 (IL-4) is an immunoregulatory cytokine produced by activated T lymphocytes to promote the growth and differentiation of cells that participate in immune defense. This study demonstrates the rapid activation...
10.
Hammack J, Kotanides H, Rosenblum M, Posner J
Neurology
. 1992 Oct;
42(10):1938-43.
PMID: 1407576
We reviewed clinical findings and serologic data on 18 men and three women with paraneoplastic cerebellar degeneration (PCD) associated with Hodgkin's disease (HD). The patients were 20 to 77 years...