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X Jimenez

Explore the profile of X Jimenez including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 9
Citations 100
Followers 0
Related Specialties
Oncology
Hematology
General Medicine
Top 10 Co-Authors
L Witte
Z Zhu
D Lu
P Bohlen
H Zhang
H Kotanides
K Hattori
F Popota
M Gomez
R TEJADA
Published In
Leukemia
Cancer Lett
Cancer Res
An Sist Sanit Navar
J Immunol Methods
Affiliations
Soon will be listed here.
Recent Articles
1.
[Transfer support and coordination of critical patients during the COVID-19 pandemic by a regional command center]
Trenado J, Sola S, Campos O, Morales J, Azeli Y, Jimenez X
Med Intensiva . 2022 Oct; 47(5):293-295. PMID: 36248279
No abstract available.
2.
[Ultrasound practice in emergency medicine. Stubborn reality when the radiologist is missing]
Gomez M, Baro A, Rodriguez A, Onaga H, Camps T, Jimenez X
An Sist Sanit Navar . 2019 Dec; 42(3):367-368. PMID: 31859275
No abstract available.
3.
The effects of aging on dopaminergic neurotransmission: a microPET study of [11C]-raclopride binding in the aged rodent brain
Hoekzema E, Herance R, Rojas S, Pareto D, Abad S, Jimenez X, et al.
Neuroscience . 2010 Oct; 171(4):1283-6. PMID: 20937365
Rodent models are frequently used in aging research to investigate biochemical age effects and aid in the development of therapies for pathological and non-pathological age-related degenerative processes. In order to...
4.
Cell-based selection of internalizing fully human antagonistic antibodies directed against FLT3 for suppression of leukemia cell growth
Williams B, Atkins A, Zhang H, Lu D, Jimenez X, Li H, et al.
Leukemia . 2005 Jun; 19(8):1432-8. PMID: 15931264
FMS-like tyrosine kinase 3 (FLT3) receptor is highly expressed in an array of hematological malignancies including approximately 90% of acute myelogenous leukemia (AML). Ligand stimulation of the receptor promotes the...
5.
Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity
Zhu Z, Hattori K, Zhang H, Jimenez X, Ludwig D, Dias S, et al.
Leukemia . 2003 Mar; 17(3):604-11. PMID: 12646950
Vascular endothelial growth factor (VEGF) and its receptors (VEGFR) have been implicated in promoting solid tumor growth and metastasis via stimulating tumor-associated angiogenesis. We recently showed that certain 'liquid' tumors...
6.
Complete inhibition of vascular endothelial growth factor (VEGF) activities with a bifunctional diabody directed against both VEGF kinase receptors, fms-like tyrosine kinase receptor and kinase insert domain-containing receptor
Lu D, Jimenez X, Zhang H, Wu Y, Bohlen P, Witte L, et al.
Cancer Res . 2001 Oct; 61(19):7002-8. PMID: 11585724
Vascular endothelial growth factor (VEGF) binds to and mediates its activity mainly through two tyrosine kinase receptors, VEGF receptor 1 [or fms-like tyrosine kinase receptor (Flt-1)] and VEGF receptor 2...
7.
An efficient route to the production of an IgG-like bispecific antibody
Zuo Z, Jimenez X, Witte L, Zhu Z
Protein Eng . 2000 Jun; 13(5):361-7. PMID: 10835110
Production of IgG-form bispecific antibody (BsAb-IgG) by co-expressing two antibodies in transfected cells is often inefficient owing to the unwanted pairing between the component heavy and light chains. We have...
8.
Acquired antagonistic activity of a bispecific diabody directed against two different epitopes on vascular endothelial growth factor receptor 2
Lu D, Kotanides H, Jimenez X, Zhou Q, Persaud K, Bohlen P, et al.
J Immunol Methods . 1999 Dec; 230(1-2):159-71. PMID: 10594363
Bispecific antibody (BsAb) technology has been successfully used as a means to construct novel antibody (Ab) molecules with increased avidity for binding, by combining two Ab or their fragments directed...
9.
Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody
Zhu Z, Lu D, Kotanides H, Santiago A, Jimenez X, Simcox T, et al.
Cancer Lett . 1999 Jun; 136(2):203-13. PMID: 10355750
The kinase insert domain-containing receptor (KDR) is the human vascular endothelial growth factor (VEGF) receptor responsible for the mitogenic and angiogenic effects of VEGF. There is much experimental evidence to...