B Pytowski
Overview
Explore the profile of B Pytowski including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
510
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0
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Recent Articles
1.
Brazel C, Ducceschi M, Pytowski B, Levison S
Mol Cell Neurosci
. 2001 Oct;
18(4):381-93.
PMID: 11640895
The FLT3 receptor tyrosine kinase (FLT3) was originally identified on hematopoietic stem cells (HSCs) and its ligand (FL) induces HSC proliferation. As stem cells originating from various tissues are more...
2.
Ludwig D, Lorenz J, Dejana E, Bohlen P, Hicklin D, Witte L, et al.
Mamm Genome
. 2000 Nov;
11(11):1030-3.
PMID: 11063261
Murine vascular endothelial cadherin-2 (VE-cad-2) is a cellular adhesion molecule that is distinct from vascular endothelial cadherin 1 (VE-cad-1) in that it does not interact with catenins and does not...
3.
Lu D, Kussie P, Pytowski B, Persaud K, Bohlen P, Witte L, et al.
J Biol Chem
. 2000 May;
275(19):14321-30.
PMID: 10799512
The kinase domain receptor (KDR) of vascular endothelial growth factor (VEGF) is the main human receptor responsible for the angiogenic activity of VEGF. The extracellular region of KDR is comprised...
4.
Prewett M, Huber J, Li Y, Santiago A, OConnor W, King K, et al.
Cancer Res
. 1999 Oct;
59(20):5209-18.
PMID: 10537299
Tumor angiogenesis is mediated by tumor-secreted angiogenic growth factors that interact with their surface receptors expressed on endothelial cells. Vascular endothelial growth factor (VEGF) and its receptor [fetal liver kinase...
5.
Pytowski B, Hicklin D, Kornhaber G, Dellaratta D, Witte L
Arch Biochem Biophys
. 1998 Nov;
359(2):310-9.
PMID: 9808774
Protein kinases play a major role in the regulation of cellular growth. We isolated a murine cDNA encoding a novel serine/threonine kinase (referred to as mSLK) ubiquituously expressed during all...
6.
Witte L, Hicklin D, Zhu Z, Pytowski B, Kotanides H, Rockwell P, et al.
Cancer Metastasis Rev
. 1998 Oct;
17(2):155-61.
PMID: 9770111
Biological evidence suggests that interference with the function of the angiogenic growth factor receptor VEGFR2 (flk1/KDR) is a particularly promising strategy to inhibit tumor-induced angiogenesis. Proof of concept was established...
7.
Zhu Z, Rockwell P, Lu D, Kotanides H, Pytowski B, Hicklin D, et al.
Cancer Res
. 1998 Aug;
58(15):3209-14.
PMID: 9699643
A single-chain antibody phage display library was constructed from spleen cells of mice immunized with a soluble form of a human vascular endothelial growth factor (VEGF) receptor, kinase insert domain-containing...
8.
Moore K, Pytowski B, Witte L, Hicklin D, Lemischka I
Proc Natl Acad Sci U S A
. 1997 Apr;
94(8):4011-6.
PMID: 9108096
Primitive hematopoietic stem cells are closely associated with discrete in vivo microenvironments. These "niches" are thought to provide the molecular signals that mediate stem cell differentiation and self-renewal. We have...
9.
Shapiro F, Pytowski B, Rafii S, Witte L, Hicklin D, Yao T, et al.
J Hematother
. 1996 Dec;
5(6):655-62.
PMID: 9117254
The Flk-2/flt3 ligand (FL) was evaluated and compared with c-kit ligand (KL) for its in vitro proliferative effects on CD34+ cells from human fetal liver, umbilical cord blood, bone marrow,...
10.
Rose C, Rockwell P, Yang J, Pytowski B, Goldstein N
Hybridoma
. 1995 Oct;
14(5):453-9.
PMID: 8575794
The flk-2 tyrosine kinase receptor is expressed on hematopoietic stem cells and on acute leukemias (AML and ALL). We have isolated a rat monoclonal antibody (71E1) that binds to this...